摘要
目的探讨慢性阻塞性肺病(COPD)患者急性加重期甲状腺激素水平的变化及临床意义。方法 189例COPD患者分为急性加重期组(A组,62例)和缓解期组(B组,127例)。健康志愿者70例设为对照组(C组)。采用化学发光免疫法检测三组血清四碘甲状腺原氨酸(T4)、三碘甲状腺原氨酸(T3)、游离四碘甲状腺原氨酸(FT4)、游离三碘甲状腺原氨酸(FT3)及促甲状腺素(TSH)水平。结果 A组T3、T4、FT3水平均显著低于B组和C组(P<0.05);而B组和C组T3、T4、FT3、FT4和TSH水平差异无统计学意义(P>0.05)。结论 CPOD病情加重期患者血清甲状腺激素水平明显降低,可用于COPD急性加重期患者病情及预后的评估。
Objective To explore the changes and significance of thyroid hormones in the patients of chronic obstructive pulmonary disease with acute exacerbation（AECOPD）.Methods Serum levels of thyroxine（T3）,triiodothyronine（T4）,free thyroxin（FT3）,free triiodothyronine（FT4） and thyroid stimulating hormone（TSH）were detected in the patients with AECOPD（group A,62 cases）,COPD patients in remission（group B,127cases）and healthy volunteers（group C,70cases）.Results Serum levels of T3,T4and FT3 were lower in group A than those in groups of B and C（P〈0.05）,which were not significantly different between groups of B and C（P〈0.05）.Conclusion Serum levels of thyroid hormones in the patients with AECOPD are abnormally reduced,which may be taken as the indicators for predicting the severity and prognosis of AECOPD patients.
出处
《江苏医药》
CAS
北大核心
2013年第15期1810-1811,共2页
Jiangsu Medical Journal
关键词
慢性阻塞性肺病
甲状腺激素
Chronic obstructive pulmonary disease
Thyroid hormones
