摘要
目的探讨扩张型心肌病(DCM)伴或不伴肺高血压患者临床特征。方法选取65例DCM患者。其中超声诊断伴肺高血压者38例,不伴肺高血压者27例。分析两者基本临床资料、心功能、超声心动图及血清总胆红素和肌酐水平等指标的差异。结果伴肺高血压DCM患者一般临床资料与不伴肺高血压DCM患者比较差异无统计学意义(P>0.05)。伴肺高血压DCM患者的纽约心功能分级Ⅲ、Ⅳ级者明显增多,左心室舒张末径、左心房内径、右心室内径、右心房内径显著扩张,左心室射血分数明显下降,胸腔积液、心包积液发生率明显增高,血清胆红素水平明显增高,与不伴肺高血压DCM患者相比较差异有统计学意义(P<0.01)。血清肌酐水平两者差异无统计学意义(P>0.05)。结论伴肺高血压的DCM患者心脏扩张较明显,心功能分级与左心室射血分数下降明显,肝脏功能损伤明显,预后较差。
Objective To investigate the clinical features of dilated cardiomyopathy（DCM） patients with or without pulmonary hypertension（PH）.Methods 65 cases of DCM were selected,38 cases with PH and 27 cases of DCM without PH by ultrasound diagnosis.Clinical data,heart function,echocardiography and serum total bilirubin and creatinine levels of all patients were analyzed.Results No statistical difference was found between the DCM patients with PH clinical data and the DCM patients without PH（P 0.05）.The DCM patients with PH who had New York heart association function classification Ⅲ,Ⅳ level were obviously increased.Left ventricular end-diastolic diameter,left atrium diameter,right ventricular diameter and right atrium diameter significant expansion,left ventricular ejection fraction decreases obviously,pleural effusion and pericardial effusion incidence increased obviously,serum bilirubin level increased significantly.Compared with the DCM patients without PH there was statistical difference（P 0.01）.The serum creatinine levels had no statistical difference（P 0.05）.Conclusion DCM patients with PH have obvious heart expansion,whose heart function classification and the left ventricular ejection fraction significantly decreased with obvious liver damage and poor prognosis.
出处
《安徽医药》
CAS
2013年第8期1360-1361,共2页
Anhui Medical and Pharmaceutical Journal
关键词
扩张型心肌病
肺高血压
超声心动图
血清胆红素
dilated cardiomyopathy
pulmonary hypertension
echocardiography
serum bilirubin
