摘要
急性肾损伤是指不超过3个月的。肾脏功能或结构方面的异常，包括血、尿、组织检测等方面的肾损伤标记物异常。本病治疗包括药物和肾脏替代疗法，后者的主要治疗目标是去除内源性和外源性毒物、炎症介质和致病因子，维持水电解质酸碱平衡，等待肾功能恢复。肾脏替代疗法主要模式包括问断血液透析、连续性肾脏替代疗法、腹膜透析、血浆置换、血液灌流。本文对小儿急性肾损伤肾脏替代治疗的时机、模式选择、适应证和常见技术问题作简要介绍。
Acute kidney injury （AKI） is defined as ＂functional and structural disorder or signs of re- nal damage including any defect from blood and urine test, or tissue imaging that is less than 3 months＂. The current treatment for AKI includes therapeutic agents and renal replacement therapy （RRT）. The goal of RRT is to remove endogenous and exogenous toxins, inflammatory mediator, pathogenic factor, and to maintain flu-id, electrolyte, and acid-base balance until renal function returns. The principal methods of RRT include inter-mittent hemodialysis, continuous renal replacement therapy, peritoneal dialysis, plasmaphresis exchange and hemoperfusion. In this article, we discussed the timing, choice of therapeutic mode, indication and common technical issues of RRT in pediatric AKI.
出处
《中国小儿急救医学》
CAS
2013年第4期348-351,共4页
Chinese Pediatric Emergency Medicine
关键词
急性肾损伤
肾脏替代疗法
儿童
Acute kidney injury
Renal replacement therapy
Children
