摘要
目的探讨检测多囊卵巢综合征(PCOS)患者糖耐量、性激素以及胰岛素临床意义。方法选择PCOS患者50例作为研究组,根据体质量指数(BMI)不同分为研究A组(BMI<25kg/m2)和研究B组(BMI≥25kg/m2),进行性激素5项检测以及糖耐量和胰岛素释放试验,同时选取同期50例健康体检者进行对比分析。结果研究组LH、FSH、PRL以及T均明显升高,而E2明显下降。研究B组1h和2h后SG和INS水平明显高于对照组,且高于研究A组,两组对比差异均具有统计学意义(P<0.05)。结论性激素水平升高和肥胖是PCOS患者的重要临床特征,肥胖可加重患者的胰岛素抵抗以及高胰岛素血症的严重程度,治疗时应根据患者的BMI情况采取不同的治疗方案。
Objective To investigate the clinical significance of sex hormones,glucose tolerance and insulin in patients with polycystic ovary syndrome（PCOS）.Methods 50 PCOS patients in our hospital were selected as research group.Based on the body mass index（BMI）,they were divided into group A（BMI 25 kg/m2） and group B（BMI ≥ 25 kg/m2）.The sex hormone detection as well as glucose tolerance and insulin release test were processed.Meanwhile,50 healthy people were selected as control group.Results The LH,FSH,PRL and T level were significantly elevated in research group,while the E2 decreased.The SG and INS level was significantly higher in research group B after 1 h and 2 h than that of group A,and the difference was statistically significant（P0.05）.Conclusion Elevated levels of sex hormones and obesity are the important clinical features of PCOS.Obesity can increase insulin resistance and the severity of hyperinsulinemia.The treatment should be based on the patient′s BMI.
出处
《国际检验医学杂志》
CAS
2013年第13期1684-1685,共2页
International Journal of Laboratory Medicine
关键词
多囊卵巢综合征
葡糖耐量试验
性腺甾类激素
胰岛素
polycystic ovary syndrome
glucose tolerance test
gonadal steroid hormones
insulin
