摘要
目的:探讨血清性激素各项检测指标与不同年龄段的多囊卵巢综合征(PCOS)患者的关系及其临床意义。方法:以月经周期正常的健康妇女为对照组,采用化学发光法测定30岁以下年龄组和30岁及以上年龄组PCOS患者促黄体生成素(LH)、促卵泡生成素(FSH)、泌乳素(PRL)、雌二醇(E2)、睾酮(TESTO)、孕酮(Prog)水平,通过统计学软件进行比较分析。结果:多囊卵巢综合征患者,30岁以下年龄组和30岁及以上年龄组LH高于对照组(P<0.01),E2高于对照组(P<0.05),TESTO高于对照组(P<0.01)。30岁以下PCOS患者组和30岁及以上PCOS患者组各检测指标之间差异无统计学意义(P>0.05)。结论:血清中LH,E2高水平及TESTO增高可能是多囊卵巢综合征的预示因子,高LH、高E2、高雄激素血症可能是引起PCOS发生的因素之一。
Objective:To investigate the relationship between the levels of serum sex hormones in different age groups and the polycystic ovary syndrome (PCOS) patients and clinical significance. Methods:PCOS patients were divided into two groups: younger than 30-year-old age group and older than 30-year-old age group. Women with normal menstruation as the control group were divided into the two corresponding age group. The levels of LH, FSH, PRL, E2, TESTO and Prog of all subjects were detected using chemiluminescence, and compared through statistical analysis software. Results:The levels of LH, E2 and TESTO of PCOS patients groups of younger 30- year-old and older than 30-year-old were higher than those in control group ( P 〈0.01, P〈0.05 and P 〈0.01, respectively). There were no significant differences of LH, FSH, PRL, E2, TESTO and Prog levels of PCOS patients between younger 30 year-old group and older than 30-year-old group ( P 〉0.05). Conclusion: The high ser um levels of LH, E2, and TESTO may be predictive factors of PCOS. High levels of LH, E2 and androgen may be one of the pathogenic factors of PCOS.
出处
《临床血液学杂志(输血与检验)》
CAS
2009年第2期204-206,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)