摘要
目的 探讨急性脑血管病和老年性痴呆症血清髓鞘碱性蛋白 (MBP)的含量变化及其临床意义。方法 采用MBP ELISA法对 2 0例急性脑出血、2 8例急性脑梗死、10例老年性痴呆症患者及 2 1名正常对照者血清MBP进行检测。结果 3组患者血清MBP含量均显著高于正常对照组 (P <0 .0 5 ) ;8例急性脑出血患者治疗前后其MBP含量有显著性差异 (P <0 .0 5 )。结论 血清MBP检测有助于急性脑出血、急性脑梗死。
Objective To investigate the changes of serum myelin basic protein (MBP) and its clinical application to patients with acute cerebral hemorrhage (ACH), acute cerebral infarction (ACI) and senile dementia(SD). Methods Serum levels of MBP were detected by enzyme linked immunoabsorbent assay (ELISA) in 58 patients including 20 ACH, 28 ACI, 10 SD, and 21 healthy vo lunteers (the normal control). Results Comparison of results of various groups indicated that serum mean MBP valucs of ACH, ACI and SD were higher than that in the normal control (P<0.05). The serum MBP valucs in patients with ACH (8 cases) before treatment were statistically higher than that in patients after treatment (P<0.05).Conclusion Detection of serum MBP can be used for the diagnosis and monitoring efficacy of the treatment of ACH, ACI and SD.
出处
《苏州医学院学报》
2000年第7期633-634,共2页
Acta Academiae Medicinae Suzhou
关键词
髓鞘碱性蛋白
急性脑血管病
老年性痴呆症
myelin basic protein
acute cerebrovascular disease
senile dementia
