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解毒化瘀汤灌洗治疗大鼠慢性骨髓炎的疗效观察 被引量:12

Observation of Therapeutic Effects of Lavage Extractant from Jiedu Huayu Decoction on Rat Chronic Osteomyelitis
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摘要 目的 :观察解毒化瘀汤灌洗治疗大鼠慢性骨髓炎的疗效。方法 :建立慢性骨髓炎动物模型 ,随机分成 3组 :中药组、抗菌溶液组及生理盐水组 ,闭式灌洗治疗 1月 ,按设计分期观察白细胞计数、血清溶菌酶含量、骨 X线、病理组织学等指标。结果 :中药组与生理盐水组之间有非常显著性差异 ( P<0 .0 1 ) ;在血清溶菌酶、骨 X线指标方面 ,中药组明显优于抗菌溶液组 ( P<0 .0 5)。结论 :解毒化瘀汤有效抑制慢性骨髓炎的发展过程 ,可能与其提高机体免疫能力有关。 Objective:To observe ther effects extractant from Jiedu Huayu decoction on lavaging chronic osteomyelitis rat models.Methods:Chronic osteomyelitis model S D rats animals were randomly divided into 3 groups:extractant from jiedu Huayu decoction group,antisepitc solution group and normal saline group.All were lavaged for 1 month.The comparative observation of model animals were taken through blood leukocyte count,serum lusozyme activity,bone X rays,roentgenography and histological manifestation at the fixed time.Results:Great significant contrast were found between the results of extractant from Jiedu Huayu decoction group and those of normal saline group (P<0.01).Contrasted the results of extractant from Jiedu Huayu decoction group with antiseptic solution group,differences were made clear in respects of serum lusozyme activity and bone X rays (P<0.05).Conclusion:Extractant from Jiedu decoction preventing effectly chronic osteomyelitis deterioration may be related to its improving the organism immune function.
出处 《中国中医骨伤科杂志》 CAS 2000年第4期18-20,共3页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金 福建省卫生科研基金!( W9711)
关键词 解毒化瘀汤 灌洗治疗 慢性骨髓炎 中医药疗法 Jiedu Huayu decoction Lavage therapy Chronic osteomyelitis Experiment research
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  • 1陈民钧,临床微生物学最新资料,1996年,1期,2页
  • 2马纪平,中华医学检验杂志,1996年,19卷,186页
  • 3李光辉,国外医学.内科学分册,1994年,21卷,390页
  • 4娄永新,实用临床细菌学检验与进展,1993年,55页

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