摘要
海南省 1994～ 1999年共报告 173例急性弛缓性麻痹 (AFP)病例 ,其中 47例分离出非脊髓灰质炎 (脊灰 )肠道病毒 (NPEV) ,NPEV分离阳性率为 2 7 17%。经鉴定 ,所有分离出的NPEV可分为柯萨奇病毒 (Coxsackie ,Cox .)A9( 1例 )、Cox .B2 ( 2例 )、B3 ( 1例 )、B6( 2例 ) ,埃柯病毒 (Entericcytopathichumanorphanvirus,ECHO) 11个型 ( 3 1例 ) ,肠道病毒 (EV) 70、71型 (各 1例 ) ,“腺病毒 ?”( 3例 ) ,尚有 5例无法分型。其中男性病例占 68 0 9% ,发病以小年龄组为主 ,3岁以下的病例占 87.2 3 % ,95 .74%的患者口服脊灰疫苗 (OPV)免疫史≥ 3次。海南省NPEV感染引起的AFP病例的肢体麻痹 68.0 9% ( 3 2 / 47)为单瘫 ;47例AFP病例中有 2例于发病 60天后仍残留麻痹 ,分别为ECHO7和EV71型感染病例。NPEV感染是AFP病例的重要病因之一 ,应当引起临床医生、防疫工作者和儿童家长的高度重视 ,做到早诊断、早治疗、早康复。
acute flacced paralysis (AFP) cases were reported in 1994～1999 in Hainan Province. The positive isolation rate of non-polio enteroviruses(NPEV)was 27.17%(47/173). Through identification, all of the NPEV could be classified as Coxsackie virus A9(1 case), Coxsackie B2(2 cases), B3(1 case), B6(2 cases)ECHO virus 11 types(31 cases), enterovirus(EV)type 70(1 case), type 71(1 case), Adenovirus? (3 cases). However, the virus strains of 5 AFP cases could not be classified. In the 47 AFP cases, 68 09% of them were male cases. Most of the cases were children of small age groups. The ages of 87 23% cases were smaller than 3 years old. 95 74%(45/47)cases had been immunized with OPV≥3 times. 32 AFP cases who were infected by NPEV only appeared one limb paralysis. 2 of them after 60 days of disease onset had residual paralysis who were infected respectively by ECHO 7 and EV 71 viruses. NPEV infection is one of the important reasons of AFP cases. It should be noticed greatly by clinic doctors, staff of EPI and parents of children. Early diagnosis, early treatment and early recovery should be accomplished.
出处
《中国计划免疫》
2000年第4期198-200,共3页
Chinese Journal of Vaccines and Immunization
