摘要
目的观察神经节苷酯GM1治疗新生儿缺氧缺血性脑病(HIE)的疗效。方法选取了2010年11月—2012年12月该院收治确诊的缺氧缺血性脑病患儿62例,并随机的将其分为两组,即干预组和对照组各31例,对照组主要进行对症治疗,同时使用胞二磷胆碱治疗;干预组在对症治疗的基础上使用神经节苷酯GM1来进行治疗,并进行对比分析。结果两组患者在接受治疗后病情均有所好转,其中干预组和观察组进行比较,患儿在原始反射、意识障碍及肌张力恢复时间,惊厥消失时间和住院时间等方面都少于后者,同时按照评分对比,干预组要高于对照组(P<0.01)。结论神经节苷酯GM1在治疗新生儿缺氧缺血性脑病上具有较好的疗效,应该予以有效的应用和推广。
Objective To observe the efficacy of the ganglioside GMI therapeutic neonatal hypoxic-ischemic encephalopathy （HIE）. Methods From,November 2010 to December 2012 in our hospital diagnosed with hypoxic-ischemic encephalopathy 62 cases, and randomly divided into two groups, namely the intervention group and the control group, 31 cases in each control group mainly symptomatic treatment, at the same time using the citicoline treatment; intervention group used in the symptomatic treatment on the basis of ganglioside GM1 treatment, and comparative analysis. Results The patients have the condition after receiving treatment improved the intervention group and the observation group recovery time compared children in primitive reflexes, impaired consciousness and muscle tone, seizures disappear time and hospitalization time are less than after, and in accordance with the rated contrast, the intervention group than the control group （P 〈 0.01）. Conclusion Ganglioside GM1 in the treatment of neonatal hypoxic- ischemic encephalopathy has a good effect on the application and promotion should be effective.
出处
《中国卫生产业》
2013年第14期11-12,共2页
China Health Industry
