摘要
目的:观察1,6-二磷酸果糖(FDP)对新生儿缺氧缺血性脑病(HIE)的治疗作用。方法:将60例HIE患儿随机分为治疗组和对照组各30例,两组均采用支持疗法和对症处理等综合治疗,治疗组在综合治疗的基础上加用FDP治疗。结果:治疗组和对照组总有效率分别为96.67%、73.33%,两组比较差异有统计学意义(χ2=6.41,P<0.05),经一个疗程治疗后,治疗组和对照组NBNA评分分别为39.62±3.71和36.80±3.25,两组比较差异有统计学意义(t=3.12,P<0.01)。结论:FDP对新生儿HIE疗效满意,值得推广。
Objective： To observe the effect of Fructose-1,6-Diphosphate, which was used to treat newborn hypoxic-ischemic encephalopathy （HIE）. Methods： Divide 60 cases of HIE into two groups at random. Both groups were treated with the same methods, at the same time, the treatment group were added with Fructose-1,6-Diphosphate. Results： In comparison with the control group, Fructose-1,6-Diphosphate treatment group had remarkable difference in effectiveness （X^2 = 6.41, P 〈 0.05）. After a course of treatment, the difference of NBNA marks between the two groups was remarkable （ t = 3.12, P 〈 0.01 ）, Condusions： Fructose-1,6-Diphosphate has satisfactory curative effect on HIE, and is worth spreading,
出处
《儿科药学杂志》
CAS
2007年第1期45-46,共2页
Journal of Pediatric Pharmacy
关键词
1
6-二磷酸果糖
新生儿
缺氧缺血性脑病
Fructose- 1,6- Diphosphate
Newborn
Hypoxic-ischemic encephalopathy
