摘要
目的讨论血清降钙素原(PCT)对于自发性气胸患者使用抗菌药物的指导作用。方法 69例自发性气胸患者随机分为两组:A组为PCT检测指导治疗组34例,B组为常规治疗组35例。两组在进行相同常规治疗的基础上,抗菌药物的使用方面,A组以PCT检测值为判断标准,即血清PCT≥0.25ng/ml时使用抗菌药物,反之不用或停用抗菌药物;B组由医生经验性判断是否使用。记录两组患者的抗生素使用时间及费用,以及住院时间。结果 A组抗菌药物使用时间短于B组,差异具有统计学意义;抗菌药物使用费用低于B组,差异具有统计学意义。两组的住院时间无明显差异。结论自发性气胸患者根据PCT的检测指导使用抗菌药物,减少了抗菌药物的使用时间及费用,能更合理的使用抗菌药物,减少滥用抗菌药物导致的耐药。
Objective To discuss the value of procalcitonin-guided treatment on antibiotic using in pneumothorax.Methods 69 patients were randomly divided into 2 groups.Group A（34 patients） received antibiotics based on the serum procalcitonin（PCT） level.If the level of PCT was higher than or equal to 0.25ng/ml,antibiotics were used.On the contrary,antibiotics were not used.Group B（35 patients） received antibiotics based on the doctor＇s decision.All of them were received the similar based treatment.The usement of antibiotic and the length of hospitalization were recorded.Results The duration of antibiotics use in group A was shorter than that in group B（P0.05）.The cost of antibiotics was lower than that in group B（P0.05）.The length of hospitalization were similar in two group（P0.05）.Conclusion PCT guidance can reduce the length and cost of antibiotic in treatment of pneumothorax.
出处
《四川医学》
CAS
2013年第5期610-611,共2页
Sichuan Medical Journal
关键词
降钙素原
气胸
抗菌药物
procalcitonin
pneumothorax
antibiotic
