摘要
目的:评价我院外科手术患者合并医院感染的病原菌及其耐药情况,为探索有效预防和控制医院感染的措施提供参考。方法:对我院2010-2012年收治的243例发生医院感染的手术患者的年龄、性别、原发疾病、手术名称、预防性使用抗菌药物情况进行调查,并对发生医院感染的部位、病原菌及耐药性进行统计学分析。结果:我院外科手术患者发生医院感染的部位多为下呼吸道,与其他感染部位比较,其构成比有显著性差异(P<0.05);对患者所感染的病原菌进行调查发现,铜绿假单胞菌、大肠埃希菌以及金黄色葡萄球菌的感染构成比显著高于其他病原菌感染构成比(P<0.05);对病原菌进行耐药性分析,发现不同病原菌对不同抗菌药物的耐药性有显著性差异(P<0.05)。结论:对外科手术合并医院感染的患者及时进行病原学检查,根据药物敏感性试验结果选择合适的抗菌药物进行治疗,可提高疗效、减少并发症的发生。
OBJECTIVE：To evaluate pathogens of surgical operation patients with nosocomial infection in our hospital and their drug resistance,and to explore effective prevention and control measures for nosocomial infection.METHODS：243 surgical operation patients with nosocomial infection in our hospital during 2010-2012 were investigated in terms of age,sex,primary diseases,operation name,prophylactic use of antibiotics.The site of infection,pathogens and drug resistance were analyzed statistically.RESULTS：The nosocomial infection in patients with surgical operation were usually found in lower respiratory tract;compared with other parts,there was a great difference in constituent ratio （P＆lt;0.05）.The investigation of pathogenic bacteria showed that the infection ratios of Pseudomonas aeruginosa,Escherichia coli and Staphylococcus aureus were significantly higher than that of other pathogenic bacteria （P＆lt;0.05）.Analysis of drug resistance of pathogenic bacteria showed that different pathogenic bacteria had obvious different resistance to different antibiotics （P＆lt;0.05）.CONCLUSIONS：The etiology inspection should be carried out duly for surgical operation patients with nosocomial infection.According to the results of drug sensitivity test,the appropriate antibiotic therapy being chosen can improve the curative effect and reduce the incidence of complications.
出处
《中国药房》
CAS
CSCD
2013年第30期2826-2828,共3页
China Pharmacy
关键词
医院感染
病原菌
耐药性
Nosocomial infection
Pathogenic bacteria
Drug resistance
