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EMMPRIN与恶性肿瘤的研究进展 被引量:2

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摘要 细胞外基质金属蛋白酶诱导因子(EMMPRIN)也简称为CD147,EMMPRIN广泛参与胚胎以及器官形态发生、骨质重建、伤口愈合等生理过程,同时还参与呼吸、循环系统疾病、关节炎及溃疡等病理过程。大量研究表明,正常组织中EMM-PRIN的出现和调节可导致MMPs表达的升高;而在肿瘤组织中,间质细胞特别是成纤维细胞分泌MMPs的表达水平与EMMPRIN的表达相关,
作者 亢渝俊 姜政
出处 《检验医学与临床》 CAS 2013年第15期2034-2037,共4页 Laboratory Medicine and Clinic
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