摘要
目的:建立通阻颗粒质量标准。方法:采用薄层鉴别方法进行定性鉴别,运用高效液相色谱法测定芦荟苷含量。结果:确立了制剂中芦荟、甘草、诃子肉鉴别方法,通过方法学系统考察,建立了芦荟苷的含量测定方法,其芦荟苷的线性范围为0.41～2.46μg,回归方程Y=12 704X+48.84(r=0.999 9),平均加样回收率96.39%,RSD 0.76%(n=9)。结论:建立的鉴别和含量测定方法简便、准确、重复性好,适用于质量控制。
Objective： To establish the quality standards for Tongzu Granules.Method： The thin layer chromatography（TLC） was adopted for qualitative identification;aloin was detected by HPLC.Result： The identifying method of Aloe,Glycyrrhiza uralensis and Terminalia chebula were established.The determination method for the content of aloin was established.The calibration curve of aloin was liner in the range of 0.412.46 μg.The regression equation was Y = 12 704X ＋ 48.84（r = 0.999 9）.The average recovery was 96.39% and RSD was 0.76%（n = 9）.Conclusion： The method is simple,accurate and reproducible.It can be used for the quality control of Tongzu granules.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第15期89-91,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
新疆维吾尔自治区"十二五"科技重大专项(201130105-4)
