摘要
目的探讨在非增强头部CT上显示的基底动脉高密度征(HDBA)与急性后循环脑梗死患者短期预后的相关性。方法回顾性分析发病48h内行非增强头部CT检查的后循环脑梗死患者103例。根据发病14 d时美国国立卫生院卒中量表评分(NIHSS),将患者分为短期预后不良组(30例)和短期预后较好组(73例)。分析HDBA与患者短期预后的关系。其中75例在发病7 d内行头部CT血管造影(CTA)或MR血管造影(MRA)检查,分析血管病变程度与HDBA的关系。结果①预后不良组HDBA、糖尿病患者所占比率及入院时NIHSS评分高于短期预后较好组,差异均有统计学意义,P<0.01。②Binary Logistic回归分析显示,HDBA(OR=0.053,95%CI:0.013~0.213,P<0.01)和入院时NIHSS评分(OR=0.705,95%CI:0.521~0.955,P<0.05)是影响急性后循环脑梗死患者短期预后不良的独立危险因素。③75例行血管检查的患者中,28例为HDBA组,47例为非HDBA组。HDBA组和非HDBA组重度狭窄或闭塞患者所占比率分别为71.4%(20/28)和6.4%(3/47),差异有统计学意义,P<0.01。结论 HDBA可能是影响急性后循环脑梗死短期预后的参考指标。
Objective To investigate the correlation between the hyperdense basilar artery (HDBA) sign on non-enhanced head CT and the short-term prognosis of acute posterior circulation isehemic stroke. Methods A total of 103 patients with posterior circulation ischemic stroke performed non-enhanced head CT within 48 hours of onset were analyzed retrospectively. The patients were divided into either a short-term poor prognosis group (n = 30) or a short-term good prognosis group (n = 73) according to the National In-stitutes of Health Stroke Scale (NIHSS) at day 14 after onset. The relationship between HDBA and short-term prognosis of the patients was analyzed. 75 patients performed head CT angiography or MR angiography (MRA) examination within day 7 after onset. The relationship between the degree of vascular lesion and HDBA was analyzed. Results ①The percentages of HDBA and diabetes as well as the NIHSS scores at admission in the short-term poor prognosis group were higher than those in the short-term good prognosis group. There were significant difference (P 〈 0.01 ). ②Binary logistic regression analysis indicated that HDBA (OR=0.053; 95%C10.013 to0.213; P〈0.01) and the NIHSS scores (OR=0.705; 95%CI 0. 521 to 0. 955 ; P 〈 0.05 ) at admission were the independent risk factors affecting short-term poor progno-sis in patients with posterior circulation ischemic stroke. ③Of the 75 patients with vascular examination, 28 were in the HDBA group and 47 were in the non-HDBA group. The percentages of the patients with se-vere stenosis or occlusion in the HDBA group and non-HDBA group were 71.4% (20/28) and 6.4% (3/47) respectively. The difference was statistically significant (P 〈 0.01 ). Conclusion HDBA was an in-dependent risk factor affecting the short-term prognosis of acute posterior circulation ischemic stroke.
出处
《中国脑血管病杂志》
CAS
2013年第7期365-368,共4页
Chinese Journal of Cerebrovascular Diseases
关键词
脑梗死
后循环缺血性卒中
基底动脉高密度征
短期预后
Brain ischemic stroke
Posterior circulation infarction
Hyperdense basilar artery sign
Short-term prognosis