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喹硫平和奥氮平对分裂症睡眠结构的影响 被引量:1

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摘要 目的研究应用喹硫平(思瑞康)和奥氮平(再普乐)对精神分裂症患者睡眠结构的影响。方法选择60例我院接收的精神分裂症患者,随机分为2组,喹硫平组、奥氮平组,各30例。分别给药喹硫平和奥氮平进行治疗,同时观察患者睡眠结构,包括睡眠总时间、睡眠潜伏期、REM睡眠期、觉醒时间、醒起时间、各睡眠分期所占%(N1%、N2%、N3%、REM%),并记录在此过程中药物产生的不良反应。结果服用喹硫平和奥氮平后,分裂症患者睡眠总时间增加,觉醒时间和醒起时间缩短,N1期时间缩短,N3显著延长(P<0.05),而睡眠潜伏期和REM睡眠期无显著变化,但两种药物之间比较无显著性差异(P>0.05)。结论应用喹硫平和奥氮平可显著增加患者睡眠总时间,提高睡眠质量,效果良好。
出处 《中国医药指南》 2013年第19期237-239,共3页 Guide of China Medicine
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