摘要
目的分析并总结胃原发性神经内分泌肿瘤(NET)的临床病理特点。方法回顾性分析18例胃原发性NET的临床与病理资料。结果胃原发性NET的主要症状为上腹部不适、隐痛,部分伴有黑便。18例胃原发性NET中,NET14例,NEC3例,MANEC1例。突触素(Syn)和嗜铬粒素A(CgA)在低级别肿瘤中呈弥漫性强阳性表达,高级别肿瘤则阳性表达较弱。结论胃原发性NET病理诊断主要依靠镜下观察和免疫组织化学技术,正确的病理分型对治疗和预后评估有指导意义。
Objective To analyze and summarize the clinical pathological characteristics of primary gastric neuroen-docrine tumors （NET）. Methods 18 cases of the clinical and pathological data of primary gastric NET was retrospectively analyzed. Results The main symptoms of primary gastric NET were discomfort and dull pain on upper abdomen, as well as melena in some of the patients.In 18 cases of primary gastric NET,14 cases were NET,3 cases were NEC and 1 case was MANEC.The expressions of synaptophysin（Syn） and chromaffin granule A（CgA） were strongly positive in tumors at a low level,while they were low in tumors at a high level. Conclusion The pathological diagnosis of primary gastric NET mainly depends on the microscopic observation and immunohistochemistry,correct pathologic classification is instructive to the treatment and prognosis assessment.
出处
《中国当代医药》
2013年第21期106-107,共2页
China Modern Medicine
关键词
胃原发性肿瘤
神经内分泌肿瘤
临床病理分析
Gastric primary tumor
Neuroendocrine neoplasm
Clinical pathological analysis
