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线粒体MT-RNR1基因突变与药物性聋 被引量:9

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摘要 大多数线粒体基因突变会引起母系遗传性疾病,而线粒体MT-RNR1基因突变主要引起药物性非综合征型母系遗传性聋,其导致的耳聋为双侧、程度不等且与氨基糖苷类药物的使用有关。线粒体基因突变导致的药物性聋的防治关键在"防",通过人为干预,可以有效的减少药物性聋的发生。
出处 《听力学及言语疾病杂志》 CAS CSCD 北大核心 2013年第4期428-430,共3页 Journal of Audiology and Speech Pathology
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