摘要
目的建立温敏性滴丸中薄荷脑的含量测定方法。方法采用HP-innowax毛细管柱(30m×0.25mm×0.25mm)和FID检测器;程序升温,进样口温度为220℃;检测器温度为250℃;载气为氮气,3.0mL/min;分流比为50∶1;进样量1μL。结果薄荷脑在0.09-0.9mg范围内具有良好的线性关系。精密度试验结果薄荷脑的RSD(n=5)为0.73%,重现性试验结果薄荷脑的RSD(n=5)为1.15%,稳定性试验结果薄荷脑的RSD为0.68%,薄荷脑回收率为99.1%。结论本法简便、快速、准确,可用于温敏性滴丸的质量控制。
Objeetve To establish determination method of the content of menthol in dropping temperature sensitiuty polyethylene glycol in the dropping of menthol content determination method. Methods： HP - innowax capillary column（ 30m×0.25mm×0.25mm） and FID detector; Temperature programmed, injection port temperature of 220℃; Detecor temperature of 250℃; The carrier gas is nitrogen, 3.0 mL/min ; Split ratio for 50： 1 ; Sample quantity 1 μL. Results ： Menthol in 0.09 - 0.9mg range has a good linear relationship. The accuracy test results of menthol RSD（ n -- 5 ） is 0.73%, reproducible test results of menthol RSD（ n = 5 ） is 1.15%, stability test results of menthol RSD was 0.68%, menthol recovery was 99.1%. Conclusion： This method is simple, rapid, accurate, and can be used for the quality control of temperature sensitive dropping.
出处
《湖北中医药大学学报》
2013年第3期41-43,共3页
Journal of Hubei University of Chinese Medicine
关键词
气相色谱法
温敏性滴丸
薄荷脑
外标法
gas chromatography, dropping Temperature sensitivity, methol, external standard method
