摘要
目的探讨C反应蛋白(CRP)在慢性阻塞性肺疾病(COPD)稳定期继发肺动脉高压患者的表达。方法将133例COPD稳定期患者分为肺动脉高压组(63例)、无肺动脉高压组(70例),分别测定C反应蛋白、肺动脉收缩压、动脉血气、肺功能并进行比较分析。结果肺动脉高压组患者血清CRP水平经对数转换后与SPAP呈正相关(r=0.405,P<0.05),与动脉血氧分压、二氧化碳分压水平无相关性,与FEV1/预计值%水平呈负相关(r=-0.713,P<0.05)。结论血清CRP水平一定程度反映COPD患者稳定期继发肺动脉高压的病情。
Objective To explore the expression of C Reactive Protein（CRP） in patients with stable chronic obstructive pulmonary disease（COPD）accompanying with pulmonary hypertension.Methods 133 patients were divided into pulmonary hypertension group with 63 cases and no-pulmonary hypertension group with 70 cases.The levels of CRP,pulmonary arterial systolic pressure,arterial blood gas analysis and lung function in two groups were detected and analysed.Results The log-transformed level of CRP was positive correlated with SPAP（r=0.405,P0.05） and negative correlated with FEV1/pre%（r=-0.713,P0.05）,while it was not correlated with PaO2 and PaC2 in patients with stable COPD.Conclusion The serum level of CRP in patients with stable COPD who was complicated by pulmonary hypertension was probably an indicator of the morbid state of patients.
出处
《国际检验医学杂志》
CAS
2013年第12期1543-1544,共2页
International Journal of Laboratory Medicine
关键词
C反应蛋白
慢性阻塞性肺疾病
肺动脉高压
C reactive protein
chronic obstructive pulmonary disease
pulmonary hypertension
