摘要
目的对154对308例习惯性流产染色体核型进行分析。方法 2008-03-2012-03门诊就诊的154对习惯性流产夫妇308例,进行染色体核型和G带分析。结果 154对308例习惯性流产夫妇进行核型和G带分析分析,50例发现染色体核型异常,染色体核型异常发生率16.23%,其中男性发生染色体核型异常14例,女性发生染色体核型异常36例,男女比例1:2.57;6例臂间倒位占染色体核型异常12.00%,12例染色体变异占染色体核型异常24.00%,32例平衡易位占染色体核型异常64.00%。结论习惯性流产形成与夫妇双方染色体核型异常有着直接关系,在习惯性流产中进行染色体核型检查非常必要,可以对染色体核型异常携带者进行诊断,进行医学遗传学理论指导。
Objective 154 of 308 cases of habitual abortion chromosome karyotype analysis. Methods 2008-03-2012-03 clinics in 154 couples with habitual abortion in 308 cases, chromosome karyotype and G banding analysis. Results 154 of 308 cases of habitual abortion couples undergoing karyotype and G analysis, found in 50 cases with abnormal chromosome karyotype, abnormal karyotype in the occurrence rate of 16.23%, in which men occur abnormal chromosome karyotype in 14 cases, females have abnormal chromosome karyotype in 36 cases, the ratio of men to women 1： 2.57;6 cases of pericentric inversion of chromosome karyotype abnormalities accounted for 12%,12 cases of abnormal chromosome karyotype chromosome variation accounted for 24%,32 cases of balanced translocations of chromosome abnormalities in 64%. Conclusion Habitual abortion couples formed with abnormal karyotypes have direct relation, in habitual abortion of chromosome karyotype check is very necessary, the abnormal chromosome karyotype carriers for diagnosis, medical genetics theory.
出处
《中国实用医药》
2013年第15期16-17,共2页
China Practical Medicine
关键词
习惯性流产
染色体核型
分析
Habitual abortion
Chromosome karyotype
Analysis
