摘要
目的:探讨乙型肝炎病毒(HBV)相关性肾炎的中医证候特点与疗效。方法:36例患者均以中医四诊和西医检查予以确诊和辨证,统计分析这类患者的证候学特点。并按数字表法随机将其分为治疗组18例,对照组18例,对照组用百令胶囊治疗,治疗组用白水方治疗,观察治疗12周、24周两组患者中医证候、尿蛋白、肝功能、肾功能等变化情况。结果:HBV相关性肾炎患者最常见的症状依次为:倦怠乏力、尿有泡沫、腰膝酸软、腰痛、脘腹胀满、尿赤、面肢浮肿、大便粘滞、两目干涩、手足心热、耳鸣、口干咽燥等;体征依次为:面色晦暗、肝掌、蜘蛛痣、胁下积块等。中医证型以脾肾两虚、热毒内蕴、肾络瘀阻最为常见,其次是肝肾阴虚、肝郁脾虚证,脾肾阳虚证出现最少;同一患者可有几个证型重叠,以脾肾两虚证与湿热内蕴证、肾络瘀阻证重叠最为常见。经中药白水方治疗后,患者尿蛋白、肝肾功能及症状、体征均得到改善。结论:HBV相关性肾炎的中医证候特点本虚以脾肾为主,标实以热毒瘀毒胶结为特点。中药白水方不仅能改善患者症状,更能达到消除蛋白尿、血尿,保护肾功能的目的,且中远期疗效较为显著且持久。
Objective： To study traditional Chinese medical（TCM） syndrome characteristics and therapeutic effect analysis of hepatitis B virus-associated glomerulonephritis.Methods： First diagnose and syndrome differentiation 36 patients by TCM four diagnostic and western medicine examination,statistics analysis the syndrome characteristics of these patients,and divide the patients into treatment group（18 cases） and the control group（18cases） by random number table.The control group were treated with Bailing capsule,while the treatment group were given Baishui description.TCM syndrome,urine protein,liver function,kidney function changes were observed when 12 and 24 weeks after the treatment.Results： The most common symptoms successively were： fatigue,urine foam,sore lumbus and knees,osphyalgia,epigastria fullness,red urine,face and limbs edema,sticky stools,dryness of the eyes,feverish sensation over the palms and soles,tinnitus,slight dry mouth and throat,etc.Physical signs successively were： deficiency of spleen and kidney,internal stasis of pathogenic heat and kidney choroid obstruction were most familiar,after these were liver-kidney yin deficiency and liver-stagnation and spleen-deficiency,yang deficiency of spleen and kidney was least observed.And usually a patient would have several symptoms,especially including deficiency of spleen and kidney,internal stasis of pathogenic heat and kidney choroid obstruction.After TCM Baishui Description treatment,urine protein,liver and kidney function,symptoms and physical signs were improved.Conclusion： TCM syndrome characteristic of Hepatitis B virus-associated glomerulonephritis showed particularly in liver and kidney and in root deficiency,the feature of branch excess was toxic heat and blood stasis cementation.TCM Baishui description could improve patients’ symptoms,but also eliminated urine protein,urine blood,and protect kidney function,and the middle and long-term effects were more significant and lasting.
出处
《中西医结合肝病杂志》
CAS
2013年第3期145-147,150,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
关键词
乙型肝炎病毒相关性肾炎
尿蛋白
白水方
治疗应用
hepatitis B virus-associated glomerulonephritis
urine protein
Baishui description /therapeutic application
