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早期集束化护理预防脓毒症肠功能障碍的效果评价 被引量:11

Research of early bundles of care preventing intestinal dysfunction with sepsis
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摘要 目的评价早期集束化护理对脓毒症患者肠功能障碍的预防作用。方法将48例脓毒症患者按照随机数字表法随机分成干预组和对照组各24例,两组均按照2012年国际脓毒症指南进行治疗,对照组按照肠功能障碍常规护理方法护理,干预组加用集束化护理方案进行干预。比较两组治疗前后APACHEⅡ评分、肠功能障碍评分及血清二胺氧化酶浓度。结果干预组治疗第7天时,APACHEⅡ评分为(16.20±2.53)分,肠功能障碍评分为(1.27±0.18)分,血清二胺氧化酶浓度为(2.20±0.21)mmol/ml,对照组分别为(24.40±2.68)分,(1.95±0.27)分,(3.26±0.10)mmol/ml,差异有统计学意义(t值分别为7.04,-6.59,13.90;P〈0.05)。结论早期集束化护理能有效预防脓毒症患者肠功能障碍的发生。 Objective To evaluate the effect of early bundles of care preventing on intestinal dysfunction in patients with sepsis. Methods Totals of 48 cases sepsis patients were randomly divided into intervention group received the early bundles of care, and control group received the routine nursing. Then, the score of intestinal dysfunction, APACHE Ⅱ and detect serum diamine oxidase concentration at 1 d and 7 d after ICU admission were observed. Results The APACHE Ⅱ [ ( 16.20 ± 2.53 ) vs (24.40 ± 2.68 ) ], intestinal dysfunction score [ ( 1.27 ± 0.18 ) vs ( 1.95 ± 0.27 ) ] and serum diamine oxidase concentration [ ( 2.20 ± 0.21 ) vs (3.26 ± 0.10)mmoL/ml ] on the 7 d in intervention group were significantly lower than those in control group, with statistically significant differences ( t = 7.04, - 6.59,13.90, respectively ; P 〈 0. 05 ). Conclusions The early bundles of care can effectively prevent the occurrence of intestinal dysfunction in patients with sepsis.
作者 吕丰梅 杜娟
出处 《中华现代护理杂志》 2013年第15期1770-1772,共3页 Chinese Journal of Modern Nursing
基金 深圳市盐田区科技局资助项目(201207023)
关键词 脓毒症 肠功能障碍 集束化护理 Sepsis Intestinal dysfunction Bundles of care
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