期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

子宫肉瘤治疗新进展 被引量：5

New Advances of the Treatment of Uterine Sarcoma
暂未订购
导出
摘要 子宫肉瘤是一种少见的子宫恶性肿瘤,恶性程度高,易局部复发及远处转移,预后不佳。手术为主要的治疗方法,强调术后治疗的规范化及个体化。术后放射治疗并不能改善子宫平滑肌肉瘤患者的无瘤生存率和整体生存率,辅助性化疗因能提高子宫癌肉瘤患者的整体生存率而成为标准治疗方案。曲贝替定用于治疗晚期子宫平滑肌肉瘤有效且安全。靶向药物治疗子宫肉瘤仍处于研究探索阶段。 Uterine sarcoma is a rare uterine malignant tumor with a high grade of malignancy and pool prognosis,which is easy to have local recurrence and distant metastasis.Surgery as the main treatment,emphasizes the standardization and individuation.Postoperative radiation treatment does not improve both disease-free survival rate and overall survival rate of uterine leiomyosarcomas patients.Adjuvant chemotherapy can improve overall survival rate of carcinosarcomas patients,therefore it is considered as the standard of therapeutic regimen.Trabectedin has demonstrated effective and reasonably safe for patients with advanced uterine leiomyosarcomas.The medical target therapy of uterine sarcoma is still at the exploratory stage.
作者 李桂兰 曲芃芃
机构地区 天津市中心妇产科医院
出处 《国际妇产科学杂志》 CAS 2013年第3期262-265,共4页 Journal of International Obstetrics and Gynecology
关键词 子宫 平滑肌肉瘤 肉瘤 子宫内膜间质 癌肉瘤 妇科外科手术 辅助疗法 Uterus Leiomyosarcoma Sarcoma endometrial stromal Carcinosarcoma Gynecologic surgical procedures Neoadjuvant therapy
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

参考文献27

  • 1D'Angelo E,Prat 1. Uterine sarcomas: a review[J]. Gynecol Oncol, 2010,116(1): 131-139.
  • 2Kapp DS, ShinJY ,ChanJK. Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas: emphasis on impact of lym?phadenectomyand oophoreclDmy[J]. Cancer, 2008, 112( 4) : 820-830.
  • 3Brown L. Pathology of uterine malignancies[J]. Clin Oncol (R Coll Radiol) ,2008,20(6) :433-447.
  • 4Ayhan A,Aksan G,Gultekin M,et al. Prognosticators and the role of lymphadenectomy in uterine leiomyosarcomas[J]. Arch Gynecol Obstet, 2009 ,280( 1) : 79-85.
  • 5Jung SI, Shin SS, Choi C, et al. Endometrial stromal sarcoma pre?senting as prevesical mass mimicking urachal tumor[J].J Korean Med Sci, 2009,24(3) : 529-531.
  • 6Iin Y, Pan L, Wang X, et al. Clinical characteristics of endometrial stromal sarcoma from an academic medical hospital in China[J]. IntJ Gynecol Cancer ,2010 ,20(9) : 1535-1539.
  • 7Nemani D,Mitra N,Guo M. Assessing the effects oflymphadenec?tomy and radiation therapy in patients with uterine carcinosarcoma: a SEER analysis[J]. Gynecol Oncol, 2008, 111 (1) : 82-88.
  • 8Galaal K,Godfrey K,Naik R,et al. Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma[J]. Cochrane Database Syst Rev, 2011 , (1 ) : CD006812.
  • 9H:.ne3ley HD, Filiaci V, Mmkman M, et at. Phase ill trial cl ifosfamide with or without paclitaxel in advanced uterine carcinosarcoma: a Gynecologic Oncology Group StudylJ]. Clin Oncol ,2007 ,25(5): 526-531.
  • 10Powell MA,Filiaci VL,Rose PG,et al. Phase II evaluation of paclitaxel and carboplatin in the treatment of carcinosarcoma of the uterus: a Gynecologic Oncology Group study[J].J Clin Oneol, 2010,28(16):2727-2731.

同被引文献52

  • 1魏丽惠.子宫肉瘤的处理[J].现代妇产科进展,2005,14(3):173-176. 被引量：1
  • 2Brown L. Pathdogy of uterine malignancies [ J ]. Clin 0ncol,2008, 20 (6) :433-447. DOI : 10. 1016/j. clon. 2008.04. 005.
  • 3Zhang C, Hu W, Jia N, et al. Uterine carcinosarcoma and high- risk endometrial carcinomas: a clinicopathological comparison [ J]. Int J Gynecol Cancer, 2015,25 (4) : 629-636. DOI: 10. 1097/IGC. 0000(0000000350.
  • 4Singh R. Review literature on uterine carcinosarcoma[ J ]. J Canc- er Res Ther, 2014,10 ( 3 ) :461-468. DOI : 10. 4103/0973-1482. 138197.
  • 5Galaal K, Godfrey K, Naik R, et al. Adjuvant radiotherapy and/or chemotherapy after surgery for uterine careinosarcoma [ J ] chrane Database Syst Rev, 2011, ( 1 ) : CD006812. DOI: 10 1002/14651858. CD006812.
  • 6Reed NS, Mangioni C, Matrom H, et al. Phase 1 randomized study to evaluate the role of adjuvant pelvic radiotherapy in the treatment of uterine sarcomas stage I and I1 : an European Or- ganisation forReseareh and Treatment of Cancer Gynecological Cancer Group Study( protocol 55874 ) [ J ]. Eur J Cancer, 2008, zM(6) :808-818. DOI: 10. 1016/j. ejca. 2008.01. 019.
  • 7Clayton Smith D, Kenneth Macdonald O, Gaffney DK. The impact of adjuvant radiation therapy on survival in women with uterine [J]. Radiother Oncol,2008,88(2) :227-232.
  • 8Tanner E J, Garg K, Leitao MM Jr, et al. High grade undifferentiat- ed uterine sarcoma : surgery, treatment, and survival outcomes [ J ]. Gynecol Onco1,2012,127 ( 1 ) :27-31. DOI : I0. 1016/j. ygyno.
  • 9Kho KA, Lin K, Hechanova M, et al. Risk of Occult Uterine Sar- coma in Women Undergoing Hysterectomy for Benign Indications [J]. ObstetGynecol, 2016,127 ( 3 ) : 468-473. DOI: 10. 1097/ AOG. 0000000000001242.
  • 10Galaal K, Godfrey K, Naik R, et al. Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosareoma [ J ] chrane Database Syst Rev, 2011, 19 ( 1 ) : CD006812. DOI: 10. 1002/14651858. CD006812.

引证文献5

二级引证文献10

国际妇产科学杂志
2013年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部