摘要
目的:分析我院药品不良反应(ADR)发生的特点及相关因素,为临床合理用药提供参考。方法:以我院2009-2012年上报的754例ADR为研究对象,结合Excel电子表格和手工筛选方法,从患者性别、年龄、给药途径、药品种类、ADR累及器官或系统及临床表现等方面进行分类统计、分析。结果:给药途径方面,静脉给药引起的ADR比例最高,占84.22%;药品类别方面,抗感染药引起的ADR比例最高,占44.30%;ADR所累及的器官或系统以皮肤及其附件损害占首位,占52.65%,其次是全身性损害,占15.65%。结论:我院ADR发生的主要相关因素是静脉给药和抗感染药。临床应重视ADR监测和报告工作,以促进临床合理用药,保障患者用药安全。
OBJECTIVE： To analyze the characteristics and related factors of adverse drug reactions （ADR） in our hospital, and to provide reference for rational drug use in the clinic. METHODS： 754 ADR cases in our hospital from 2009 to 2012 were in-vestigated as subject, and classified and analyzed statistically in respect of gender, age, route of administration, drug types, or-gans or systems involved in ADR and clinical manifestations, by using Excel and manual selection. RESULTS： The ratio of the ADR induced by intravenous administriation was the highest in respect of route of administration （84.22%）. Anti-infectives were the major cause of ADR in respect of drug types （44.30%）. The lesion of skin and its appendants was the main lesion in ADR cas- es （52.65 % ）, followed by the systemic damages （ 15.65 % ）. CONCLUSIONS： The occurrence of ADR cases in our hospital is relat-ed with intravenous administration and anti-infectives. ADR monitoring and reporting should be emphasized in order to promote ra- tional clinical drug administration and to ensure patients＇ safety.
出处
《中国药房》
CAS
CSCD
2013年第26期2464-2467,共4页
China Pharmacy
关键词
药品不良反应
报告
分析
合理用药
Adverse drug reactions
Report
Analysis
Rational drug use
