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贯叶连翘和乌灵菌粉提取物抗抑郁研究 被引量:2

Antidepressant Reaearch with Hypericum Perforatum and Wuling Mycelia Extracts
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摘要 本实验建立了嗅球损毁大鼠模型,以研究受试药物的药效,并探讨其治疗抑郁症的机理。本课题是研究贯叶连翘和乌灵菌粉提取物对抑郁症的治疗作用。采用嗅球损毁抑郁大鼠模型,进行了行为学测试Morris水迷宫实验,并对海马中5-HT1A和MAO含量进行了测定。这些数据均具有统计学意义(P<0.05)。 the experimental establishment of the olfactory bulb lesion rat model,to study the efficacy of drug,and to explore the mechanism of treatment of depression.This paper is a study of Hypericum perforatum and Wuling mycelia extracts on depression treatment effect.The olfactory bulb damage depression model rats,a behavioral test of Morris water maze,and on hippocampal 5-HT1A and MAO contents were determined.These data were statistically significant(P0.05).
作者 刘璐
出处 《江西中医学院学报》 2012年第6期77-78,100,共3页 Journal of Jiangxi College of Traditional Chinese Medicine
关键词 抑郁症 嗅球损毁 MORRIS水迷宫 Depression Olfactory Bulb Damage The Morris Water Maze
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