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儿童神经精神性狼疮12例影像学表现及临床分析 被引量：2

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摘要 目的探讨儿童神经精神性狼疮的临床特点与影像学的关系。方法回顾性分析我院小儿肾脏风湿免疫科2005年1月至2013年1月间收治的12例确诊儿童神经精神性狼疮患儿的临床资料及影像学资料。结果12例患儿均处于狼疮重度活动期，均行头部MRI或CT检查。3例行头部CT检查，2例异常；11例行头部MRI检查，10例发现异常，弥漫型病变4例，病变主要分布在双侧大脑半球、基底节区、半卵圆中心及小脑半球，多发点、片状T1低信号、他高信号影，FLAIR与DWI表现为高信号或等信号；局灶型病变4例，表现为单一部位的T1低信号、12高信号，FLAIR及DWI表现为相同部位高信号；病变部位在大脑半球2例、脑干1例、小脑1例。脑萎缩病变1例，脑出血病变1例。结论头部MRI诊断儿童神经精神性狼疮敏感性高，抗心磷脂抗体阳性可能与系统性红斑狼疮中枢神经系统损害有密切关系。狼疮重度活动时需警惕神经精神性狼疮的发生，结合患儿病史特点、临床表现及影像学改变，除外其他原因引起的神经系统症状，早期诊断及积极治疗，患者预后可能良好。
作者 唐莹 杜悦 吴玉斌
机构地区 中国医科大学附属盛京医院小儿肾脏风湿免疫科
出处 《中国小儿急救医学》 CAS 2013年第3期302-304,共3页 Chinese Pediatric Emergency Medicine
关键词 神经精神性狼疮 磁共振成像 并发症
分类号 R747.9 [医药卫生—神经病学与精神病学]
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参考文献13

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共引文献10

同被引文献48

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二级引证文献4

中国小儿急救医学
2013年 第3期

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