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脑源性神经营养因子在精神分裂症吸烟患者中的研究进展

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摘要 本文主要依据近年国内外脑源性神经营养因子(brian-derived neurotrophic factor,BDNF)、精神分裂症吸烟和认知功能的相关文章,重点寻找和阐述BDNF、精神分裂症吸烟和认知功能三种之间的关系及其相互交互作用。
作者 惠李 张向阳 张萱
机构地区 吉林大学公共卫生学院基因组医学研究中心 吉林大学第二医学院糖尿病合并症研究中心 北京回龙观医院精神医学研究中心
出处 《国际精神病学杂志》 2013年第2期86-89,共4页 Journal Of International Psychiatry
基金 吉林大学研究生创新基金(编号:20121113) 国家自然基金(编号:81171064)资助
关键词 BDNF 精神分裂症吸烟 认知功能
分类号 R749 [医药卫生—神经病学与精神病学]
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参考文献15

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  • 4Beuten J, Ma JZ, Payne TJ , et al. Significant association of BDNF haplotypes in European-American male smokers but not in European- American female or African- American smokers. Am J Med Genet Neuropsychiatr Genet. 2005; 139B(1) :73-80.
  • 5Zhang XY, Xiu MH, Chen DC, et al. Nicotine dependence and serum BDNF levels in male patients with schizophrenia. Psychopharmacology, 2010 ; 212 ( 3 ) : 301-307.
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二级参考文献8

  • 1Li MD.The genetics of nicotine dependence[J].Curr Psychiatry Rep,2006,8(2):158-164.
  • 2Lu B,Martinowich K.Cell biology of BDNF and its relevance to schizophrenia[J].Novartis Found Symp,2008,289:119-129.
  • 3Neves-Pereira M,Cheung JK,Pasdar A,et al.BDNF gene is a risk factor for schizophrenia in a Scottish population[J].Mol Psyehiatry,2005,10(2):208-212.
  • 4Kunugi H,Ueki A,Otsuka M,et al.A novel polymorphism of the brain-derived neurotrophic factor(BDNF)gene associated with late-onset Alzheimer's disease[J].Mol Psychiatry,2001,6(1):83-86.
  • 5Cubells JF,Kobayashi K,Nagatsu T,et al.Population genetics of a functional variant of the dopamine beta-hydroxylase gene(DBH)[J].Am J Med Genet,1997,74(4):374-379.
  • 6Beuten J,Ma JZ,Payne TJ,et al.Significant association of BDNF haplotypes in European-American male smokers but not in European-American female or African-American smokers[J].Am J Med Genet B Neuropsychiatr Genet,2005,139(1):73-80.
  • 7Egan MF,Kojima M,Callicott JH,et al.The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function[J].Cell,2003,112(2):257-269.
  • 8韩军鸽,朱华,陈国弟,陈鹏,罗良鸣,刘晓妮,王程宝.不同时程吗啡依赖戒断大鼠海马CA1区BDNF及PSD-95的表达[J].四川大学学报（医学版）,2008,39(2):253-255. 被引量：3

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国际精神病学杂志
2013年 第2期

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