摘要
目的探讨血尿酸（BUA）、超敏C-反应蛋白（hs-CRP）与冠状动脉粥样硬化性心脏病（CHD）的相关性。方法选取2011年9月~2012年10月辽宁省鞍山市双山医院收治的经冠状动脉造影确诊CHD患者120例作为观察组,同时选取120例排除CHD的住院患者作为对照组,检测并比较两组患者BUA、hs-CRP水平。结果观察组BUA和hs-CRP水平显著高于对照组,两组比较差异有高度统计学意义（P〈0.01）。观察组中,急性心肌梗死患者BUA及hs-CRP水平最高。两组高尿酸血症患者的冠心病危险因子高血压、高胆固醇、高三酰甘油的发生率比较,差异均有统计学意义（P〈0.05或P〈0.01）。结论 BUA及hs-CRP水平与CHD密切相关,检测BUA及hs-CRP水平对CHD的预防、治疗、预后判断等有重要意义。
Objective To explore the relationship between blood uric acid（BUA）,high sensitive C-reactive protein（hs-CRP） and coronary heart disease.Methods 120 cases of patients diagnosed coronary heart disease by coronary an giography in Shuangshan Hospital of Anshan City from September 2011 to October 2012 were selected as the observa tion group,and 120 patients without coronary heart disease were selected as the control group.The levels of BUA and hs-CRP were examined and compared.Results The levels of BUA and hs-CRP of the observation group were higher than those of the control group,the differences were statistically significant（P ＆lt; 0.01）.In the observation group,patients with acute myocardial infarction had the highest levels of BUA and hs-CRP.The incidence rates of coronary heart disease risk factors including high pressure,high cholesterol and high triglyceride had significant differences be tween the patients with hyperuricemia in the two groups（P ＆lt; 0.05 or P ＆lt; 0.01）.Conclusion The serum levels of BUA and hs-CRP were closely related to coronaty heart disease.It is significant to determine the serum levels of BUA and hs-CRP for the prevention,treatment and prognosis of coronary heart disease.
出处
《中国医药导报》
CAS
2013年第17期97-98,共2页
China Medical Herald
关键词
冠心病
血尿酸
超敏C-反应蛋白
相关性
Coronary heart disease
Serum uric acid
High sensitive C-reactive protein
Correlation
