期刊文献+

幽门螺杆菌与基因组不稳定性

原文传递
导出
摘要 1983年Warren与Mashall首次从胃黏膜中分离出幽门螺杆菌(Helicobacter pylori,Hp),此后国内外学者对Hp感染与胃十二指肠疾病的关系做了大量研究。Hp感染作为体内最常见的一种慢性感染,与胃癌关系较为密切,1994年国际癌症研究机构(IARC)将Hp列为Ⅰ类致癌因子。然而,Hp确切的致癌机制仍不十分清楚,给胃癌防治带来巨大困难。
作者 谢川 吕农华
出处 《中华内科杂志》 CAS CSCD 北大核心 2013年第6期519-520,共2页 Chinese Journal of Internal Medicine
基金 国家自然科学基金(81270479)
  • 相关文献

参考文献2

二级参考文献28

  • 1Dian-Chun Fang Shi-Ming Yang Xiao-Dong Zhou Dong-Xu Wang Yuan-Hui Luo Department of Gastroenterology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China.Telomere erosion is independent of microsatellite instability but related to loss of heterozygosity in gastric cancer[J].World Journal of Gastroenterology,2001,7(4):522-526. 被引量:35
  • 2Martins C,Kedda MA,Kew MC.Characterization of six tumorsuppressor genes and microsatellite instability in hepatocellular carcinomain southern African blacks[J].World Journal of Gastroenterology,1999,5(6):470-476. 被引量:21
  • 3Fuchs CS, Mayer RJ. Gastric carcinoma. N Engl J Med 1995;333:32-41.
  • 4Parente F, Caselli M, Bianchi Porro G. Gastric apoptosis and Helicobacter pylori infection: an intricate matter. Scand J Gastroenterol 2001; 2:113-115.
  • 5Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, Sibley RK. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991; 325:1127-1131.
  • 6Blaser MJ, Chyou PH, Nomura A. Age at establishment of Helicobacter pylori infection and gastric carcinoma, gastric ulcer,and duodenal ulcer risk. Cancer Res 1995; 55:562-565.
  • 7Berloco P, Russo F, Cariola F, Gentile M, Giorgio P, Caruso ML, Valentini AM, Di Matteo G, Di Leo A. Low presence of p53 abnormalities in H pylori-infected gastric mucosa and in Kastric adenocarcinoma. J Gastroenterol 2003; 38:28-36.
  • 8Wang XW, Tseng A, Ellis NA, Spillare EA, Linke SP, Robles AI, Seker H, Yang Q, Hu P, Beresten S, Bemmels NA, Garfield S, Harris CC. Functional interaction of p53 and BLM DNA helicase in alOolotosis. J Biol Chem 2001; 276:32948-32955.
  • 9Aaltonen LA, Peltomaki P, Leach FS, Sistonen P, Pylkkanen L, Mecklin JP, Jarvinen H, Powell SM, Jen J, Hamilton SR,Leach FS. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260:812-816.
  • 10Bowcock A, Osborne-Lawrence S, Barnes R, Chakravarti A,Washington S, Dunn C. Microsatellite polymorphism linkage map of human chromosome 13q. Genarnics 1993; 15:376-386.

共引文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部