摘要
目的探讨介入治疗在围绝经期功血的应用。方法双侧子宫动脉栓塞+卡铂子宫动脉灌注治疗围绝经期功能失调性子宫出血,一方面减少子宫动脉的血液灌注达到止血的目的,另一方面卡铂药物通过阻止DNA的转录与复制,从而抑制子宫内膜的增生从而达到治疗功血的目的。24例围绝经期功血并发不同程度贫血患者采用介入治疗。结果 24例患者均成功完成介入治疗,术后无严重并发症发生,术后40～89 d后月经来潮,经量明显减少,随访6～18个月均未再次出现大量出血。结论介入治疗为围绝经期功血治疗提供了一条安全、创伤小、保留女性生殖系统完整性、避免长期药物治疗的副反应的可靠途径。
Objective To Study on interventional treatment in the application of perimenopausal dysfunctional uterine bleeding. Methods Bilateral uterine artery embolization of uterine artery perfusion plus carboplatin in treatment of perimenopausal dysfunctional uterine bleeding. On one hand, reduce the blood perfusion of uterine artery to hemosta- sis. On the other hand, carboplatin drugs through the transcription and replication block DNA, thereby inhibiting en- dometrial hyperplasia so as to achieve the purpose of treatment of uterine bleeding. All 24 patients with peri- menopausal dysfunctional uterine bleeding complicated with different degree of anemia were treated with interventional therapy. Results All 24 patients were successfully completed the intervention, without serious postoperative complica- tions, after 40-89 days after menstruation, menstrual volume decreased significantly, the follow-up of 6-18 months, all did not appear again massive hemorrhage. Conclusion Interventional therapy for perimenopausal dysfunctional uterine bleeding treatment provides a safe, less trauma, retained the female reproductive system integrity, to avoid a reliable way to long-term adverse effects of drug treatment.
出处
《中国现代医生》
2013年第16期145-146,共2页
China Modern Doctor
关键词
双侧子宫动脉行栓塞化疗
围绝经期功血
介入治疗
卡铂
Bilateral uterine artery embolization chemotherapy
Perimenopausal dysfunctional uterine bleeding
Inter- ventional therapy
Carboplatin
