摘要
目的探讨急性心肌梗死(AMI)伴室性期前收缩患者窦性心律震荡和心率变异性(HRV)的变化和临床意义。方法随机选取本院AMI合并室性期前收缩的患者58例(心梗组)和体检健康者52例(对照组)。收集所有受检者24h平均心率、R-R间期标准差、窦性心律震荡的初始值(TO)、窦性心律震荡的斜率(TS)、肌钙蛋白I(TNI)峰值、左室射血分数(LVEF)。比较两组24h平均心率、R-R间期标准差、TO、TS。并研究窦性心律震荡和HRV指标与TNI峰值和LVEF的相关性。结果心梗组的心律震荡和HRV指标弱于对照组,差异有统计学意义(P<0.05)。心梗组的R-R间期标准差与TNI峰值呈负相关(r=-0.52,P<0.01),与LVEF呈正相关(r=0.25,P<0.05)。TO与TNI峰值呈正相关(r=0.68,P<0.01),TO与LVEF呈负相关(r=-0.49,P<0.01)。TS与TNI峰值呈负相关(r=-0.79,P<0.01),TS与LVEF呈正相关(r=0.55,P<0.01)。死亡组的R-R间期标准差、TS低于存活组,TO高于存活组,差异有统计学意义(P<0.05)。结论窦性心律震荡和HRV减弱是反映AMI严重程度和预后的有用指标。
Objective To investigate change of sinus heart rate turbulence and heart rate variability（HRV） in patients with acute myocardial infarction（AMI） companied with ventricular premature systole.Methods In 58 randomly selected patients with systolic hospital AMI with ventricular premature（MI group） and 52 cases of healthy persons（control group）.Collect all the subjects 24h average heart rate,R-R interval standard deviation,sinus rhythm turbulence initial value（TO）,sinus rhythm turbulence slope（TS）,cardiac troponin I（TNI） peak,left ventricular ejection fraction（LVEF）.Comparison of two groups of 24h average heart rate,R-R interval standard deviation,TO,TS.Correlation study of sinus rhythm turbulence and HRV index and the TNI peak and LVEF.Results MI group of heart rate turbulence and HRV index was significantly weaker than that of the control group,the difference was statistically significant（P〈0.05）.MI group R-R interval standard deviation was negatively correlated with the peak value of TNI（r=-0.52,P〈0.01）,and was positively correlated with LVEF（r=0.25,P〈0.05）.Positive correlation was found between TO and TNI peak（r=0.68,P〈0.01）,TO was negatively correlated with LVEF（r=-0.49,P〈0.01）.TS and TNI peak was negatively correlated（r=-0.79,P〈0.01）,TS was positively correlated with LVEF（r=0.55,P〈0.01）.Death group of R-R interval standard deviation,TS was significantly lower than that in the survival group,TO was significantly higher than the survival group,the difference was statistically significant（P〈0.05）.Conclusion Sinus rhythm turbulence and HRV weakened is useful index to reflect the severity and prognosis of AMI.
出处
《实用心脑肺血管病杂志》
2013年第6期48-49,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
心肌梗死
窦性心律震荡
心律变异性
Myocardial infarction
Sinus heart rate turbulence
Heart rate variability
