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高血压、高血压并糖尿病患者心率变异性及其临床意义 被引量:1

The Heart Rate Variability and its Clinical Significance in Hypertensive and Hypertensive Combined Diabetic Patients
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摘要 目的测定高血压及合并糖尿病患者心率的变异性情况。方法38例高血压患者,18例高血压合并糖尿病患者和18例健康对照者,用动态心电图仪测定24hRR间期的变异性(HRV)。结果心率变异性在试验对象明显降低,尤其合并有糖尿病者。随访发现心血管事件的发生率在试验组为16.7%,而健康组为0;心血管事件组的HRV明显低于无心血管事件组。以HRV的3种指标而论,发生心血管事件组都明显高于无发生心血管事件组3种指标,预测心血管事件的敏感性为55%~66%,特异性为82%~95%,准确性为78%~91%。 Aim\ To investigate the heart rate variability in patients with hypertension and hypertension complicated with diabetes.\ Methods\ By using Holter 24 h R R intervals variability analysis system, the heart rate variability(HRV) was measured in 38 patients with essential hypertension(EH). 18 patients with essential hypertension complicated with diabetes(EHCD) and 24 normal controls(NC) were compared.\ Results\ The HRV of patients with EH and EHCD is markedly depressed,being more remarkable in the later group. Follow up investigation found that the incidence of cardiovascular events(CVE) is 16.07% in EH and EHCD group, whereas without any cases was found in NC group. The HRV of CVE group is obviously lower than non CVE group. Regarding the three parameters of HRV, the positive rates of them in CVE group are higher than those of non CVE group,the sensitivity for predicting CVE is 55.55% ̄66.66%, the specificity is 82.97%~95.74%,the accuracy is 78.57%~9 07%.\ Conclusion\ The decreased HRV correlate to CVE and may have important value for assessing prognosis of the patients with EH and EHCD.
出处 《高血压杂志》 CSCD 1996年第3期215-216,共2页 Chinese Journal of Hypertension
关键词 心律变异性 高血压 心血管事件 heart rate variability\ essential hypertension\ cardiovescular events
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