摘要
当前国内外正在积极研究一种非侵袭性产前诊断方法———从母体外周血分离胎儿细胞进行产前诊断。孕母外周血中存在微量胎儿细胞。采用各种先进的分离富集方法 ,可获得胎儿细胞 ,通过对这些细胞进行分析 ,即可获得产前诊断信息。该技术仍处在研究阶段 ,尚存在一些问题需要解决 ,故目前还不能广泛应用于临床 ,但它的应用前景非常光明。
In recent years,considerable progress has been achieved in nonivasive prenatal diagnosis using fetal cells isolated from maternal blood.Many kinds of fetal cells have been found in maternal blood,but they are often present in very small numbers.Fetal cells can be isolated and enriched from maternal blood by many advanced methods.Fetal chromosomal abnormalities,fetal sex,fetal RHD blood type and so on can be detected on isolated fetal cells.In current,there are many unanswered problems about this technique,but the outlook for nonivasive diagnosis in the future is optimistic.
出处
《现代诊断与治疗》
CAS
2000年第5期274-277,共4页
Modern Diagnosis and Treatment
关键词
孕母外周血
胎儿细胞
产前诊断
Maternal blood
Fetal cells
Prenatal diagnosis
