8Chidambaram SB, Muthiah R. Post-ischemic administration of nimodipine following focal cerebral isehemic-reperfusion injury in rats alleviated excitotoxicity, neurobehavioural alterations and partially the bioenergetics[J]. Int J Devl Neuroscience, 2011,29 : 93-105.
9Rice JE, Vannucci RC, Brierley JB. The influence of immaturity on hypoxici schemic brain damage in the rat[J]. Ann Neurol, 1981,9 : 131-141.
10Loria F, Petrosino S, Hernangomez M, et al. An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis[J]. Neurobiology of Disease, 2010, 37 : 166-176.
3Sveinsson 0 A, Kjartansson O, Valdimarsson E M.Cerebral ischemia/infarction-epidemiology, causes and symptoms[ J]. Laeknabladid ,2014,100(5 ) :271-275.
4Borst P, Schinkel A H. P-glycoprotein ABCBI:a major player in drug handling by mammals[ J ]. J Clin Invest, 2013,123(10) :4131-4136.
5Yano K, Takimoto S, Motegi T, et al. Role of P- glycoprotein in regulating cilnidipine distribution to intact and ischemic brain[J]. Drug Metab Pharmacokinet,2014,29 ( 3 ) :254-258.
6Tsai M J, Tsai S K, Hu B R, et al. Recovery of neurological function of ischemic stroke by application of conditioned medium of bone marrow mesenchymal stem cells derived from normal and cerebral ischemia rats [J]. J Biomed Sci,2014,21 (5) :2-7.
7Longa E Z, Weinstein P R, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats[ J]. Stroke, 1989,20( 1 ) :84-90.
8Kitagawa K, Matsumoto M, Tagaya M, et al. ' Ischemic tolerance'phenomenon found in the brain [ J ]. Brain Res, 1990,528( 1 ) :21-25.
9Huls M, Russel F G, Masereeuw R. The role of ATP binding cassette transporters in tissue defense and organ regeneration[ J]. J Pharmacol Exp Ther,2009,328 ( 1 ) : 3-8.
10Ktinig J, MUller F, Fromm M F. Transporters and drug- drug interactions: important determinants of drug disposition and effects [ J ]. Pharmacol Rev, 2013,65 ( 3 ) :944-950.