摘要
目的 :比较磁刺激运动诱发电位 ( MEP)与电刺激 MEP在刺激方式、信号特征和临床意义等方面的异同。方法 :2 0只雄性 SD大鼠经静脉麻醉后采用 Mag2型磁刺激仪和 Cantada型肌电图仪分别进行单次经颅磁及电刺激 ,观察不同刺激强度下 ,在 T1 2 硬膜外和双侧前肢伸肌和后肢腓肠肌记录的 MEP变化特征。结果 :磁刺激脊髓 MEP先正后负 ,以 P1 或 N1 波最显著 ,波形不够稳定 ,个体间差异较大 ,随着刺激强度增大 ,MEP潜伏期缩短 ,波幅增大。近阈值电刺激 MEP与相应的超强磁刺激 MEP潜伏期相近 ,波幅也相差不大。结论 :采用单次磁或电刺激 MEP仍能客观反映脊髓运动传导束的功能状态 ,电和磁刺激的 MEP之间存在一定程度的同源成分 。
Objective: To compare the stimulation parameters, the signal characteristics and the clinical implication of the magnetic motor evoked potentials (MEP) and electric MEP. Methods: During intravenous anesthesia, twenty male SD rats received single transcranical magnetic and electric stimulation with Mag 2 stimulator and Cantada electromyograph. The characteristics of MEP recorded epidurally or in the bilateral forelimbs′ extensor muscles and hindlimbs′ gastrocnemius muscles under different stimulation intensities were observed. Results: Magnetic MEP consisted of positive peaks followed with negative peaks, among which the P 1 or N 1 were remarkable. It had unstable waveform and great individual variance. Its latency decreased and its amplitude increased with the increase of stimulation intensity. The latency and amplitude of MEP elicited by near threshold electric stimulation were similar to that of MEP evoked by super intensive magnetic stimulation. Conclusion: MEP elicited by single magnetic or electric stimulation can reflect the functional status of the motor tracts in the cord. Some co origin components exist between electric MEP and magnetic MEP, which can be used as the comparative foundation for the clinical and experimental researches.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2000年第7期625-628,共4页
Academic Journal of Second Military Medical University
基金
上海市医学领先专业重点学科基金资助项目 !( 1995- 0 0 8
1998- - 0 0 8)
关键词
运动诱发电位
磁刺激
电刺激
脊髓
大鼠
motor evoked potentials
magnetic stimulation
electric stimulation
spinal cord
