摘要
目的试图从理论上提出辐射生物效应多样性的辐射剂量生物效应理论,建立统一的全剂量辐射生物效应理论模型,定量描述和解释辐射生物效应的多样性。方法总结提出辐射剂量生物效应理论的6个原理的基础上,建立统一剂量辐射生物效应理论模型。结果提出辐射生物效应多样性的辐射剂量生物效应理论,建立了8个辐射剂量生物效应方程,可以定量描述和解释辐射生物效应的多样性。结论建立的辐射剂量生物效应理论和理论模型,定量描述和解释辐射剂量生物效应:一般损伤效应、低剂量兴奋性效应、旁效应和超敏效应。该理论和理论模型适用于其它广义刺激:物理因子、化学因子、生物因子、心理、药物、毒物、信息等剂量生物效应关系,可称为广义刺激剂量生物效应理论模型,具有重要的学术意义和应用价值。
Objective Try to put forward of the radiation dose biological effects theory of radiation biological effects diversity, a unified whole dose radiation biological effects theory model, quantitative description and explain the diversity of bi- ological effect of radiation. Methods Based on the summary of six princples of radiation dose biological effects theory, estab-lish the unified uniform dose radiation biological effects theory model. Results Having put forward radiation biological effects diversity of radiation dose biological effects theory and set up eight radiation dose biological effects equation, the diversity of biological effects of radiation can be described quantificationally and explained. Conclusions The establishment of radiation dose biological effects theory and the theory model, quantitative description and interpretation of radiation dose biological effects ： general damage effects, low dose hormesis effect , bystander effect and hyper - radiosensitivity. The theory and theo-retical model is suitable for the other generalized stimulation ： physical factors, chemical factors and biological factors, psycho-logical factors, drugs, toxicans, information isodose biological effects relations, which can be called generalized stimulus dose biological effect theory model, which is of important academic significance and application value.
出处
《中国辐射卫生》
2013年第1期5-7,共3页
Chinese Journal of Radiological Health
基金
全军医学科学技术研究"十一五"计划专项基金资助项目:06Z014
关键词
辐射剂量
生物效应
低剂量兴奋作用
旁效应
超敏效应
Radiation Dose
Biological Effectt
Low dose Hormesis Effect
Bystander Effect
Super Sensitive Effect
