摘要
目的：探讨iDOSE（iDOSE,Philips）技术降低肝脏肿瘤患者增强CT辐射剂量的能力。材料与方法：选择肝脏肿瘤患者200例进行常规及低剂量肝脏增强CT扫描。患者随机分成4组（A、B、C、D组）,A组常规剂量扫描,滤波反投影（FBP）重建图像,B、C、D组增强扫描门脉期管电流分别较常规降低30%、50%、70%,iDOSE重建图像。定量计算4组图像噪声及对比噪声比（CNR）。对4组图像的诊断信息（肿瘤锐利度、肿瘤与正常肝脏组织对比度、图像主观噪声、图像总体质量）按1~4分（1分最差,4分最优）予以评分。采用完全随机设计的方差分析及秩和检验（Kruskal Wallis）对结果进行比较。结果：客观评估中,iDOSE重建各组的噪声均低于A组（P〈0.01）;CNR均高于A组（P〈0.01）。主观评估中,4组图像之间肿瘤与正常肝脏组织对比度、主观噪声无差异（P=0.09,P=0.74）;肿瘤锐利度及图像总体质量评估中B、C组与A组之间无差异,而D组低于A组（P〈0.01）。结论：对于肝脏肿瘤患者增强CT检查,iDOSE迭代重建技术可使在管电流较常规剂量降低50%的条件下,仍得到与常规剂量FBP重建相当甚至更好的图像质量。
Objective： To assess the ability of iDOSE（iDOSE,Philips） iterative reconstruction technique for low-dose hepatic enhanced CT.Materials and Methods： 200 patients with diagnosis of liver tumors were randomly divided into four groups（A,B,C,D）.Patients in group A were scanned with routine-dose CT,reconstructed with filtered back projection（FBP）.While patients in group B,C,D were scanned with 30%,50% and 70% radiation dose reduction CT respectively,reconstructed with iDOSE reconstruction.Quantitative noise and contrast-to-noise（CNR） measurements were performed.Qualitative ranking of sharpness of tumors,contrast between tumors and normal liver tissue,noise,and image quality were graded（scale： 1（worse）-4（best））.Data was analyzed using completely randomized design analysis of variance and Kruskal Wallis test.Results： In the comparison of quantitative noise,the groups with iDOSE reconstruction were lower than group A（P0.01）.CNR of groups with iDOSE reconstruction were higher than group A（P0.01）.There was no significant difference among the four groups for tumor tissue contrast and qualitative noise score（P=0.09,P=0.74）.There was no significant difference between group B and A,C and A for tumor sharpness and image quality scores.However,a significant difference in tumor sharpness and image quality scores was observed beween group D and group A（P0.01）.Conclusions： When the radiation dose of hepatic enhanced CT scan was reduced by 50%,images maintaining the diagnostic quality of routine dose CT or even better images could be acquired with iDOSE technique.
出处
《中国临床医学影像杂志》
CAS
2013年第5期334-337,345,共5页
Journal of China Clinic Medical Imaging
