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中年男性饮酒与血脂异常关系的病例-对照研究 被引量:10

Alcohol consumption and dyslipidemia risk: a case-control study in middle-aged men
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摘要 目的探讨饮酒对中年男性血脂的影响。方法选取2011年6月至2012年6月于山东大学第二医院住院或体检的30~65岁男性,221例血脂异常患者作为病例组,233例血脂正常者作为对照组,对研究对象进行问卷调查和体格检查。采用单因素和非条件多因素Logistic回归分析饮酒与血脂异常的关系。结果与对照组比较,随着每日酒精摄入量的增加血脂异常患病危险增加,OR值分别为:1.52(≤25g/d)、1.83(25~50g/d)、3.11(>50g/d);TG异常危险随饮酒量的增加而升高,OR值分别是:1.98(≤25g/d)、2.79(25~50g/d)、4.37(>50g/d)。Logistic回归分析显示平均每日酒精摄入量(g/d)(OR=1.007,95%CI1.002~1.012)是血脂异常的危险因素。结论饮酒可能是中年男性血脂异常的危险因素。 Objective To explore the relationship between alcohol consumption and risk of dyslipidemia in middle-aged men.Methods Male patients of dyslipidemia(n=221) were chosen as the case group,while normal ones(n=233) as the contrast group.All study objects were aged 30-65 years old,came from in hospital or made physical examination at the Second Hospital of Shandong University from June 2011 to June 2012.Question test and physical examination were made for them.Single factor analysis and unconditional multi-factorial Logistic regression were performed to analyze the relationship between alcohol consumption and risk of dyslipidemia.Results Compared with the contrast group,the risk of dyslipidemia significantly increased with increasing average daily alcohol consumption,while ORs were 1.52(≤25g/d),1.83(25-50g/d),3.11(50g/d).The similar thing happened on the risk of abnormal TG levels,while ORs were 1.98(≤25g/d),2.79(25-50g/d),4.37(50g/d).The results of unconditional multi-factorial Logistic regression analysis indicated that the average daily alcohol consumption(g/d)(OR=1.007,95%CI 1.002-1.012)was a risk factor of dyslipidemia.Conclusion Alcohol consumption may be a risk factor of dyslipidemia in middle-aged men.
出处 《卫生研究》 CAS CSCD 北大核心 2013年第3期437-441,共5页 Journal of Hygiene Research
关键词 饮酒 血脂异常 病例-对照研究 alcohol dyslipidemia case-control study
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