摘要
目的了解吉林省延边朝鲜族自治州(延边州)丙型肝炎(丙肝)病毒(Hepatitis C Virus,HCV)感染的危险因素,为预防控制丙肝提供参考。方法采用病例-对照研究的方法,以性别和年龄作为匹配因素,按照1∶1的配对原则选择研究对象,开展相应的问卷调查和血清学检测,以确定HCV感染的危险因素。结果单因素分析显示,病例组和对照组在家庭成员是否有HCV感染者、纹眉(眼线、唇线)、是否去洗浴场所、是否去理发店修面、是否使用安全套、手术史、输血史、输血时间、针灸史、口腔诊疗史、内窥镜史方面差异有统计学意义(P<0.05)。多因素Logistic回归分析结果表明,进入回归方程的变量是家庭成员有HCV感染、去洗浴场所、有输血史和口腔诊疗史。结论家庭成员有HCV感染者、输血史、经常去洗浴场所、有口腔诊疗史是HCV感染的危险因素,其中在输血的时间上,1992年及以前输血感染HCV的风险高于1993年及以后。而经常使用安全套是HCV感染的保护因素。
Objective To find out the risk factors of hepatitis C infection, and provide scientific basis for prevention of hepatitis C in Yanbian prefecture. Methods risk factors are evaluated by case-control method. The subjects were selected by matching indicators of sex and age, and based on the matching principle of 1：1 between case and control groups. Results The single factor analysis showed that the history of hepatitis C infection, Eyebrow （eyeliner, lip line）, experience in bathing shop, shaving in barbershop, using condoms, history of operation, history of blood transfusion, time of blood transfusion, history of acupuncture, history of dental clinic and history of endoscope are influenced factors and two groups has significant statistic difference. Muhifactor analysis showed that history of hepatitis C infection, experience in bathing shop, history of blood transfusion and history of dental clinic are the influenced factors and two groups has significant statistic difference. Conclusion The risk factors of HCV infection are history of hepatitis C infection, experience in bathing shop, history of blood transfusion and history of dental clinic. The risk of HCV infection in the history of blood transfusion before 1992 is higher than after 1992. It is the protect factor from the HCV infection to use condoms often.
出处
《中国疫苗和免疫》
CAS
2013年第2期159-163,共5页
Chinese Journal of Vaccines and Immunization
