摘要
目的了解中国和日本两国肝细胞癌(HCC)手术患者肝炎病毒感染状况。方法查阅1995年1月至1999年12月在我国四川省成都和绵阳市3所三甲医院以及日本东京大学附属医院确诊且实施外科手术的672例HCC患者的病历,获取相关资料进行分析。结果中国HCC患者肝炎病毒感染的比例为75.53%(321/425),其中91.28%为乙型肝炎病毒(HBV)感染,中位年龄为50岁;日本HCC患者肝炎病毒感染的比例为82.59%(204/247),其中77.94%为丙型肝炎病毒(HCV)感染,中位年龄为64岁;中日两国有肝炎病毒感染的HCC患者中伴肝硬化的比例分别为89.10%(286/321)和68.14%(139/204)。结论在中国乙型肝炎病毒感染是引起HCC的重要病因,而日本的HCC则与丙型肝炎病毒感染密切相关。
Objective To describe and compare the hepatitis virus infection in hepatocellular carcinoma （HCC） patients receiving surgical operation in China and Japan. Methods Information of surgical HCC patients was retrieved from the medical records. The concerned characteristics of the HCC cases from two countries were described and compared. Results A total of 425 diagnosed cases that underwent surgical resection for HCC in China were investigated, and the corresponding cases in Japan were 247. The proportion of the hepatitis virus infection was 75.53% in patients with HCC from China. Within the infection cases, 91.28% were positive for HBsAg but negative for anti-HCV. The proportion was 82.59% in patients with HCC from Japan. Within the infection cases, 77.94% were positive for anti-HCV but negative for HBsAg. The proportion of hepatocirrhosis in the hepatitis virus infection patients with HCC were 89.10% and 68.14% in China and Japan, respectively. Conclusion The hepatitis B virus infection showed be a main cause of HCC in China, however, the HCC in Japan be mostly related to hepatitis C virus infection.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2005年第5期332-334,共3页
Chinese Journal of Preventive Medicine
