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海岛相关饮食可致病因素诱导小鼠胃粘膜损伤的研究

Experimental Study of the Island Diet Pathogenic Factors Induced Gastric Mucosal Injury in Mice
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摘要 为寻找海岛相关饮食中诱导胃粘膜损伤的致病因素,将80只小白鼠分成5组(鼠粮对照组、海产品食物搭配组、鱼胆汁污染饮食组、鱼内脏组和变质虾蟹组)进行研究。结果表明:鼠粮对照组胃粘膜正常;海产品食物搭配组2只小鼠胃粘膜轻度炎症,与其他组相比繁殖能力旺盛;鱼胆汁污染饮食组1级损伤8只占40%,2级损伤8只占40%,3级损伤4只占20%。鱼内脏组1级损伤2只占10%,2级损伤10只占50%,3级损伤8只占40%。变质虾蟹组2级损伤6只占30%,3级损伤14只占70%。寒流因素所导致的死亡率Ⅴ>Ⅳ>Ⅲ。海岛相关饮食中诱导胃粘膜损伤程度的因素为变质虾蟹组>鱼内脏组>鱼胆汁污染饮食组,胃黏膜损伤严重者在环境改变时死亡率也相应增高。 Looking for pathogenic factors of the island features diet induced gastric mucosal injury. Methods: 80 mice were divided into five groups: the control group of mice food, seafood and food with the group, the fish bile pollution diet group, fish offal group, deterioration of shrimp and crab group. Results: The normal rat grain control group gastric mucosa; the seafood food with group 2 mice mild inflammation of gastric mucosa, strong reproductive capacity compared with the other groups; the fish bile pollution diet group an injury only 40%, 2 damage only 40%, the three injuries account for only 20%. Fish offal group an injury only 10%, only 50% of two injury 10, the three injuries account for only 40%. 6 accounted for only 30%, three injury; metamorphic shrimp and crab group 2 damage 14 accounted for only 70%. Mortality caused by the cold snap factor V〉 IV〉 III. Conclusion: Tile island diet induced gastric mucosal injury factors: metamorphic shrimp and crab group〉 fish viscera group〉the fish bile pollution diet group, severe cases of gastric mucosal injury mortality in the e.nvironment changes also increase accordingly.
出处 《浙江海洋学院学报(自然科学版)》 CAS 2013年第2期129-134,共6页 Journal of Zhejiang Ocean University(Natural Science Edition)
基金 舟山市科技局2010年项目(10134)
关键词 胃粘膜 海岛饮食 变质虾蟹 鱼胆汁 污染 gastric mucosa the island diet metamorphic shrimp and crab fish bile pollution
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