摘要
目的研究玉叶金花Mussaenda pubescens.的化学成分。方法采用硅胶、sephadex LH-20、ODS柱色谱等方法进行分离纯化,根据理化性质及波谱数据鉴定化合物的结构。结果从玉叶金花正丁醇萃取部位分离鉴定了7个三萜皂苷类成分,分别为3β,19α-dihydroxyolean-12-en-28-oic acid(28→1)-β-D-glucopyranosyleste(r 1),mussaendoside R(2),mussaendoside V(3),mussaendoside M(4),mussaendoside Q(5),mussaendosideG(6),mussaendoside U(7)。结论化合物1为首次从该植物中分离得到。
Objective To study the chemical constituents from the whole plants of Mussaenda pubescens. Methods The chemical constituents from the whole plants of Mussaenda pubescens, were isolated and purified by silica column chromatography, ODS and Sephadex LH-20 column chromatography. Their structures were elucidated by chemical and spectral analysis. Results Seven compounds were obtained from n-BuOH-soluble fraction, and they were identified as 3β, 190α-dihydroxyolean-12-en-28-oic acid （28→1） - β-D-glucopyranosyl ester （1）, mussaendosidc R（2）, mussaendoside V （3）, mussaendoside M （4）, mussaendoside Q （5）, mussaendoside G （6） and mussaendoside U （7）. Conclusion Compound（ 1 ） has been obtained from the plant of Mussaenda pubescens, for the first time.
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2013年第3期278-281,共4页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
广西壮族自治区科技厅项目(桂科能12239004-2)
关键词
玉叶金花
化学成分
三萜皂苷
Mussaenda pubescens.
Chemical constituents
Triterpenoid saponins
