摘要
该文对有毒药用植物黑龙骨的化学成分进行了研究。利用大孔吸附树脂、正相和反相硅胶柱和制备型HPLC等色谱技术从中分离得到9个化合物,分别为:东莨菪内酯(1),trans-3,4-methylenedioxycinnamyl alcohol(2),syringaresinol(3),syringaresinol 4-O-β-D-glucopyranoside(4),6'-O-(E)-feruloylsucrose(5),loliolide(6),4-hydroxy-3-methoxyl-benzaidehyde(7),Δ5-pregnene-3β,17α,20α-triol(8),Δ5-pregnene-3β,17α,20α-triol-20-O-β-D-canaropyranoside(9)。并运用质谱、核磁等波谱技术对分离得到的化合物进行了结构鉴定。化合物1,2,5～7为首次从该属植物中分离得到已知化合物。
The chemical constituents of Periplocaforrestii were studied by means of macroporous resin, silica gel, ODS column chromatography and PHPLC. Nine compounds were isolated from this plant. By using ESI-MS and NMR, the structures of the nine compounds were determined as scopoletin （ 1 ）, trans-3, 4-methylenedioxycinnamyl alcohol（2）, syringaresinol （3）, syringaresinol 4-O- β-D-glueopyranoside （4）, 6＇-O-（E） -feruloylsucrose （ 5 ）, loliolide （ 6 ）, 4-hydroxy-3-methoxyl-benzaidehyde （ 7 ）, △^5-pregnene-3β, 17α, 20α-triol（8） and △^5-pregnene-3β, 17α, 20α-triol-20-O-β-D-canampyranoside（9）, respectively. Compounds 1, 2 and5-＇/are isolated from Periplocagenus for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2013年第10期1536-1538,共3页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(21132009)
关键词
黑龙骨
杠柳属
化学成分
Periploca forrestii
Periploca genus
chemical constituents
