摘要
目的 探讨影响Ⅳ期上皮性卵巢癌预后的因素。方法 回顾性分析 1990年 1月～ 1998年 5月我院治疗的 31例Ⅳ期上皮性卵巢癌的临床资料 ,包括患者年龄、病理类型、分化程度、转移部位、术后残留病灶大小、化疗疗程数及生存期等。结果 总的中位生存时间为 15个月 ,残留病灶≤ 2cm、化疗次数≥ 8、无肝实质转移的患者中位生存时间明显较相应的对照组长 (P <0 0 1) ;经多因素分析 ,年龄、病理类型、分化程度对预后无显著性影响。结论 彻底的缩瘤术、积极适宜的化疗是提高Ⅳ期上皮性卵巢癌患者生存期的必要手段。
Objective\ To determine the prognostic factors of stage Ⅳ epithelial ovarian cancer.Methods\ A retrospective review of 31 patients primarily treated in our hospital from 1990 to 1998 was conducted.Data were collected in regard to age,pathologic type,the degree of differentiation,sites of metastasis,size of residual mass,time of chemotherapy,and survival periods.Results\ The overall median survival peroids was 15 months.The median survival peroids of the groups with residual mass less than 2cm,receiving more than 8 cycles of chemotherapy,metastatic site other than liver were significantly longer(P<0 01). Age,pathologic type and differentiation degree showed no significant effects on the prognosis.Conclusion\ We suggest that the complete cytoreductive surgery and proper chemotherapy be necessary in improving the survival peroids of patients with stage Ⅳ epithelial ovarian cancer.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2000年第9期547-549,共3页
Chinese Journal of Practical Gynecology and Obstetrics
