摘要
目的 :评价骨显像和血清CA15 3RIA诊断乳腺癌骨转移的临床价值。方法 :骨显像在静脉注射99mTc MDP 3— 4小时后进行 ,CA15 3测定参考药盒说明书 ,对 6 1例乳腺癌术后全身骨显像及血清CA15 3放射免疫测定结果进行分析。结果 :9例临床及X线检查诊断为骨转移者 ,骨显像及CA15 3测定均为阳性 ,其中骨显像示多发病灶 7例 ,单发病灶 2例。 15例骨显像及CA15 3测定均阳性 ,而X线平片检查阴性病例中 ,后经CT检查证实骨转移者 6例 (5例骨显像示多个病灶 ,1例为单个病 )。 12例骨显像阳性而CA15 3测定阴性病例中 ,除 5例骨转移治疗后疼痛完全缓解的病例外 ,7例病例中有 6例为手术创伤所致骨显像假阳性病例。结论 :骨显像呈多发放射性浓聚灶且血清CA15 3放射免疫测定为阳性病例 ,可确认全身有广泛骨转移。对于CA15 3阳性的骨显像示单个病灶的病例 ,应高度重视。因此 ,骨显像结合CA15 3放射免疫测定及针对性的X线检查 ,对于骨显像单发病例 ,有助于明确诊断 。
Purpose:To evaluate radionuclide bone scanning and CA15 3 RIA in patients with breast cancer for detecting bone metastasis.Methods:Radionuclide bone imaging and serum CA15 3 RIA in 61 patients with breast cancer were performed. Results:Of 24 patients elevated CA15 3 level and were detected with 99mTc MDP imaging, 12 patients with multuple bone metastases and 3 patients with single metastasis. Conclusions:The study indicates that the radionuclide boen scanning and CA15 3 RIA have hihger sensitivity for diagnosis of breast cancer with bone metastasis. The combination of bone scanning and CA15 3 RIA may be helpful to improve positive diagnostic rate.
出处
《中国癌症杂志》
CAS
CSCD
2000年第3期255-257,共3页
China Oncology
