期刊文献+

A型肉毒杆菌毒素治疗面肌痉挛235例临床研究 被引量:10

Clinical observation of therapeutic effects of botulinum toxin type A on 235 hemifacial spasm patients
暂未订购
导出
摘要 目的:探讨A型肉毒杆菌毒素(BTXA)治疗面肌痉挛(HFS)的疗效及副作用。方法:对235例HFS病人进行面肌多点注射BTXA,对治疗前后的病情分级进行比较,并随访12—36周。结果:BTXA治疗的总有效率为98.3%(231/235),无全身反应,半年复发率为60%,药效作用时间平均16周;重复注射同样有效。结论:局部注射BTXA是治疗HFS的一种有效手段。 Objective: To explore the therapeutic efficacy of botulinum toxin type A on hemifacial spasm(HFS). Methods: 235 HFS patients were beated with botulinum toxin type A and followed up. Symptomatic alleviations after the injection were graded in comparison with the symptoms at the pretreatment stage. Rusults: The efficient rate was 98. 3% (231 /235 injections) in the 235 cases. but 60% of the patients relapsed about half a year later, the duration of action was average 16 weeks; Conclusions: Botulinum toxin type A is an effective therapy for hemifacial spasm.
出处 《现代康复》 CSCD 2000年第7期1000-1001,共2页 Modern Rehabilitation
关键词 A型肉毒杆菌毒素 面肌痉挛 局部注射 疗效 botulinum toxin type A hemifacial spasm
  • 相关文献

参考文献8

  • 1Mauriello JA. Treatment of benign essential blepharospasm and hemifa cial spasm with botulinum toxin: a preliminary study of 68 patients[J].Ophthal Plastic Reconstruct Surg, 1985, 4:283
  • 2Albert W, Kim BSJ. Management of hemifacial spasm with botulinum A[M]. Jankovic J, Hallett M. Therapy of botulinum toxin. New York:Maecel Dekker, 1994. 353~359.
  • 3Jespersen JH, Dupont E, Gelineck J, et al. Hemifacial spasm: Magnetic resonance angiography[J]. Acta Neurol Scand, 1996,93(1): 3538
  • 4汤晓芙,万新华.A型肉毒毒素治疗局限性肌张力障碍与面肌痉挛[J].中华神经科杂志,1996,29(2):111-114. 被引量:117
  • 5王荫椿.肉毒毒素结构和功能的研究[J].国外医学:军事医学分册,1985,12(6):326-329.
  • 6Chen RS, Tsai CH. Botulinum toxin A injection in the treatment of hemifacial spasm[J]. Acta Neurol Scand, 1996,3:207~211
  • 7丁新华.肉毒杆菌毒素(BTX)治疗肌肉痉挛的进展[J].现代康复,2000,4(1):80-81. 被引量:6
  • 8Hott JS, Dalakas MC, Sung C, et al. Skeletal muscle specific immunotoxin for the treament of focal muscle spasm[J]. Neurology, 1998, 50(2): 485~491

二级参考文献12

  • 1Tsui J K C,Lancet,1986年,2卷,245页
  • 2Thompson NS,Baker RJ,Cosgrove AP,etal.Musculoskeletal modelling indetermining the effect of botulinum toxin on the hamstring of patients with crouchgait[J].DevMed Child Neurol,1998,40(9):622
  • 3MallV,Heinen F,Linder-M,etal.Treatment of cerebral palsy with botulinumtoxin A.:functional benefit and reduction of disability[J]. Pediatr Rehabil.1997,1(4):235
  • 4Wong.Use of botulinum toxin injection in 17 children with spastic cerebral palsy[J].Pediatr-Neurol.1998,18(2):124-31
  • 5Palmer DT,HornLy,Harmon RL.Bontulinum toxin treatment of lumbrical spasticity:a brief repor[J].Am j Phy Med Rehabil.1998,77 (4):348
  • 6Wilson DJ,Childer Mk,Cooke DL,et al.Kinematic changes following botulinum toxin injection after traumatic brain injury[J].Braininj.1997, 11(3):157
  • 7Viriyavejakul A,Vachalathiti R,Poungvarin N.Botulinum trearment for post stroke spasticity:low dose regime[J].J Med Asson Thai,1998,81 (6):413
  • 8Reiter F,Danni M,Lagalla G,etal.Low dose botulinumtoxin with ankle taping for the treatment of spastic equinovarus foot after stroke[J]. Arch Phyed Rehabil.1998.79(5):532
  • 9Richardson D,Edwards S,Sheean GL,et al.Theeffect of botulinum toxin on hand function after incomplete spinal cord injury at the level of C5/6:aCasereport[J].Clin Rehabil.1997,11(4):288
  • 10Inagj K,Ford CNBless DM,et al.Analysis of factors affecting botulinum toxin results inspasmodic dysphonia[J].J Voice.1996,10(3):30613

共引文献126

同被引文献61

引证文献10

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部