3[2]Kanaya T,Kyo S,Hanaya K,et al.Adenoviral expression of p53 reprease telomerase activity through downegution of human telomerase reverse transcriptase transcription[J].Clin Cancer Res,2000,6:1239～1247.
4[3]Counter CM,Hirte HW,Bacchetti S,et al.Telomerase activity in human ovarian carcinoma[J].Proc Natl Acad Sci USA,1994,9:2900～2904.
6Elkablawy MA, Maxwell P, Williarnson K, et al. Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival. J Pathol,2001 ; 194:436-443.
7Bum N, Shaw P, Bouzourene H, et al. Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer. Lab Invest, 2001 ;81:217-229.
8Valassiadou KE, Stcfanaki K, Tzardi M, et al. Immunohistochemical expression of p53, bcl- 2, MDM2 and wall/p21 proteins in colorectal adenocarcinomas. Anticancer Res, 1997; 17:2571-2576.
9Schumaeher U, Adam E, Feldhaus S,et al. Cell differentiation and chemotherapy influence p53 and MDM2 immunoreactivity in human HT29 colon cancer cells grown in scid mice. Cancer Lett,2001 ; 166(2):215-221.
10Goussia AC, Ioachim E, Agnantis NJ, et al. Ecl- 2 expression in colorectal turnouts. Correlation with p53, mdm - 2, Rb proteins and proliferation indies. Histol Histopathol, 2000; 15 (3) :667-672.
