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胃癌相关基因的生物信息学研究 被引量：2

Bioinformatics study on gastric cancer-re-related genes
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摘要 国外学者利用生物信息学技术和资源研究了WNT、TPARM、IGSF11、TMEM25、Tp53i5、prickle、TFF、Snail3、FMNL、CLDN23、MGC29506、MGC9753、FGFR2和FLJ10261等与胃癌有关的基因,描述和鉴定了基因的位置、结构及其mRNA与蛋白表达,有利于寻找胃癌诊断、治疗和预防的靶点。 This overview was about the bioinformatics study of some new gastric cancer-related genes as WNT, TPARM, IGSF11, TMEM25, Tp53i5, prickle, TFF, Snail3, FMNL, CLDN23, MGC29506, MGC9753, FGFR2, FLJ10261. They were identified by using microarray and bioinformatics, their structure, locus, mRNA transcription and protein expression were also studied. The results suggested that some genes（or proteins） maybe applied as the targets for early diagnosis and drug delivery of gastric cancer.
作者 郑长黎 文继舫
机构地区 中南大学基础医学院
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2005年第16期2460-2463,共4页 China Journal of Modern Medicine
关键词 生物信息学 癌基因 抑癌基因 胃癌 bioInformatics tumor suppressor gene oncogene gastric cancer
分类号 R735.2 [医药卫生—肿瘤]
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二级参考文献15

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共引文献16

同被引文献10

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中国现代医学杂志
2005年 第16期

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