摘要
目的：应用免疫固定的电泳技术，提高M蛋白病的正确诊断率。方法：通过对血清免疫球蛋白定量、区带电泳、固定电泳以及尿的区带电泳、免疫电泳和本周氏蛋白的检测，综合分析判断。结果：检测来自国内送诊的1213例标本，共检出M蛋白445例，占36．69％，准确率达99．6％。结论：以免疫固定电泳替代传统的检测方法，使得鉴定M蛋白的方法较2年前有了更大的提高。
Objective: Using immunofixation electrophoresis (IFE)techniques to improve the diagnostic accuracy for monoclonal gammapathies. Methods: Based on the rephormetric assay of serum immunoglobulins and the ratio of light chain in patients, zone electrophoresis, immunofixation electrophoresis were performed to detect MM in serum; qualitative determination of Bence Jones protein in urine and concentrated urinary protein immunoelectrophoresis were included to confirm the results. Results:445 monoclonal gammapathies from 1 213 clinical specimens of China were detected. The detect rate was 36.69% .The accuracy rate was 99.6%. Conclusion: Combined usage of several methods can get more accurated results in the detection of MM.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2000年第7期387-389,共3页
Chinese Journal of Immunology
关键词
M蛋白病
免疫固定电泳
游离轻链
诊断
Monoclonal gammapathies Immunofixation electrophoresis Free light chain
